Variability in subcortical aphasia is due to variable sites of cortical hypoperfusion

A variety of fluent and nonfluent aphasias have been reported after left basal ganglia stroke. It has been speculated that this heterogeneity may reflect variations in cortical hypoperfusion resulting from large vessel stenosis. To test this hypothesis, a consecutive series of 24 patients with left...

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Bibliographic Details
Published in:Brain and language 2004-06, Vol.89 (3), p.524-530
Main Authors: Hillis, Argye E., Barker, Peter B., Wityk, Robert J., Aldrich, Eric M., Restrepo, Lucas, Breese, Elisabeth L., Work, Melissa
Format: Article
Language:English
Subjects:
Adult
Adult and adolescent clinical studies
Aged
Aged, 80 and over
Aphasia
Aphasia - classification
Aphasia - etiology
Aphasia - pathology
Basal Ganglia Cerebrovascular Disease - complications
Basal Ganglia Cerebrovascular Disease - pathology
Basal ganglia stroke
Biological and medical sciences
Cerebral Infarction - complications
Cerebral Infarction - pathology
Cerebrovascular disease/stroke
Etiology
Female
Humans
Hypothesis Testing
Language Fluency
Language Tests
Magnetic Resonance Imaging
Male
Measures (Individuals)
Medical sciences
Middle Aged
Neurological Impairments
Organic mental disorders. Neuropsychology
Patients
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Regional Blood Flow
Subcortical aphasia
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Description
Summary:A variety of fluent and nonfluent aphasias have been reported after left basal ganglia stroke. It has been speculated that this heterogeneity may reflect variations in cortical hypoperfusion resulting from large vessel stenosis. To test this hypothesis, a consecutive series of 24 patients with left caudate infarct identified with diffusion-weighted imaging underwent language testing and perfusion-weighted imaging
ISSN:0093-934X
1090-2155
DOI:10.1016/j.bandl.2004.01.007