Relationship between the prenatal exposure to low-level of mercury and the size of a newborn’s cerebellum

Abstract Exposure to methylmercury at any stage of central nervous system development could induce alterations and result in severe congenital abnormalities. Total mercury level in maternal hair during pregnancy correlates well with blood levels of methylmercury and with total mercury levels in feta...

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Bibliographic Details
Published in:Medical hypotheses 2011-04, Vol.76 (4), p.514-516
Main Authors: Cace, I. Bilic, Milardovic, A, Prpic, I, Krajina, R, Petrovic, O, Vukelic, P, Spiric, Z, Horvat, M, Mazej, D, Snoj, J
Format: Article
Language:English
Subjects:
Adult
Cerebellum - drug effects
Cerebellum - growth & development
Child
Female
Hair - chemistry
Humans
Infant, Newborn
Internal Medicine
Maternal Exposure
Methylmercury Compounds - analysis
Methylmercury Compounds - toxicity
Organ Size
Pregnancy
Prospective Studies
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Summary:Abstract Exposure to methylmercury at any stage of central nervous system development could induce alterations and result in severe congenital abnormalities. Total mercury level in maternal hair during pregnancy correlates well with blood levels of methylmercury and with total mercury levels in fetal brain. A prospective study has been conducted and a total of 137 childbearing women living at the coastal region with term, normal pregnancies were included and their newborns evaluated by ultrasonography. Mothers and their newborns are divided in two groups according to their hair mercury levels; examined group with high body levels of mercury (⩾1 μg/g) and control group with low body levels of mercury (
ISSN:0306-9877
1532-2777
DOI:10.1016/j.mehy.2010.12.005