Effect of Training Judo in the Competition Period on the Plasmatic Levels of Leptin and Pro-inflammatory Cytokines in High-Performance Male Athletes

The purpose this study was to evaluate the effect of training judo in the competition period on the plasmatic levels of bioactive molecules in high-performance male athletes. The subjects were divided into two groups, a trained group with 11 judokas and a nontrained group also with 11 subjects. Bloo...

Full description

Saved in:
Bibliographic Details
Published in:Biological trace element research 2010-06, Vol.135 (1-3), p.345-354
Main Authors: de Oliveira, Donizete Cicero Xavier, Rossano Procida, Izildinha, das Neves Borges-Silva, Cristina
Format: Article
Language:English
Subjects:
Adaptations
Athletes
Biochemistry
Biomedical and Life Sciences
Biotechnology
Chemokine CCL2 - blood
Cytokines
Exercise - physiology
Humans
Interleukin-6 - blood
Leptin - blood
Life Sciences
Male
Males
Martial arts
Martial Arts - physiology
Nutrition
Oncology
Plasma
Training
Tumor Necrosis Factor-alpha - blood
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The purpose this study was to evaluate the effect of training judo in the competition period on the plasmatic levels of bioactive molecules in high-performance male athletes. The subjects were divided into two groups, a trained group with 11 judokas and a nontrained group also with 11 subjects. Blood samples obtained 60 h after training to measure plasma tumor necrosis factor (TNF-α), interleukin-6 (IL-6), monocyte chemotactic protein 1 (MCP-1), and leptin levels. The trained group presented a significant reduction in the percentage of fat and fat mass and an increase in the lumbar and lower limbs traction forces and the maximum VO₂ when compared to the nontrained group. There was no significant difference in the serum concentrations of TNF-α and IL-6 between the two groups. The trained group presented a lower concentration of leptin, both as absolute values as well as relative to the percentage of fat, and a higher concentration of MCP-1, in relation to the nontrained group. Our results suggest an adaptation in the capacity of synthesizing and secreting leptin in response to chronic stress in judo, what suggests a neuro-hormonal adjustment that guarantees the efficiency of metabolism. The changes of MCP-1 indicated a possible inflammatory state.
ISSN:0163-4984
1559-0720
DOI:10.1007/s12011-009-8499-2