Calcium Increase in the Mammillary Bodies with Aging

To elucidate compositional changes of the mammillary body with aging, the authors investigated age-related changes of elements, relationships among their elements, and gender differences in the mammillary bodies by direct chemical analysis. After ordinary dissection at Nara Medical University was fi...

Full description

Saved in:
Bibliographic Details
Published in:Biological trace element research 2010-06, Vol.135 (1-3), p.56-66
Main Authors: Suwannahoy, Patipath, Tohno, Setsuko, Mahakkanukrauh, Pasuk, Minami, Takeshi, Tohno, Yoshiyuki
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Aging
Aging - physiology
Biochemistry
Biomedical and Life Sciences
Biotechnology
Calcium
Calcium - metabolism
Chemical analysis
Female
Humans
Life Sciences
Magnesium - metabolism
Male
Mammillary Bodies - metabolism
Nitric acid
Nitric oxide
Nutrition
Oncology
Phosphorus
Phosphorus - metabolism
Spectrometry
Sulfur - metabolism
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c458t-43cd50379a01dfe1073267e3cc0a431ca773481021f31ac92c81bf0f5638419a3
cites cdi_FETCH-LOGICAL-c458t-43cd50379a01dfe1073267e3cc0a431ca773481021f31ac92c81bf0f5638419a3
container_end_page 66
container_issue 1-3
container_start_page 56
container_title Biological trace element research
container_volume 135
creator Suwannahoy, Patipath
Tohno, Setsuko
Mahakkanukrauh, Pasuk
Minami, Takeshi
Tohno, Yoshiyuki
description To elucidate compositional changes of the mammillary body with aging, the authors investigated age-related changes of elements, relationships among their elements, and gender differences in the mammillary bodies by direct chemical analysis. After ordinary dissection at Nara Medical University was finished, the mammillary bodies were resected from the cerebra of the subjects. The subjects consisted of 19 men and 25 women, ranging in age from 70 to 101 years (average age = 83.8 ± 7.2 years). After ashing of the mammillary bodies with nitric acid and perchloric acid, element contents were determined by inductively coupled plasma-atomic emission spectrometry. It was found that the Ca content increased slightly and significantly in the mammillary bodies with aging, but the P, S, Mg, Zn, Fe, and Na contents did not change significantly with aging. Regarding the relationships among elements, significant correlations were found among the contents of Ca, P, S, and Mg in the mammillary bodies, with one exception between P and Mg contents. With regard to the seven element contents, no significant gender differences were found in the mammillary bodies.
doi_str_mv 10.1007/s12011-009-8491-x
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_856759320</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2023186271</sourcerecordid><originalsourceid>FETCH-LOGICAL-c458t-43cd50379a01dfe1073267e3cc0a431ca773481021f31ac92c81bf0f5638419a3</originalsourceid><addsrcrecordid>eNqFkU1PGzEQhi3UCkLgB3BpV71w2nbG4_XHEaKWIqXqoXC2jOMNRtldamdV-u9xtJGQOMDJBz_va888jJ0hfEUA9S0jB8QawNRaGKyfDtgMm8bUoDh8YDNASbUwWhyx45wfAFBxQ4fsCI2URiHOmFi4jY9jV133PgWXQxX7ansfql-u6-Jm49L_6nJYxZCrf3F7X12sY78-YR9bt8nhdH_O2e2P7zeLn_Xy99X14mJZe9HobS3IrxogZRzgqg0IirhUgbwHJwi9U4qERuDYEjpvuNd410LbSNICjaM5O596H9Pwdwx5a7uYfSi_6sMwZqsbqRpDHN4llZCckzDyfZLIkEKpC_nlFfkwjKkvA1uOWnAuyjLnDCfIpyHnFFr7mGJXtmYR7E6SnSTZIsnuJNmnkvm0Lx7vurB6SeytFIBPQC5X_Tqkl5ffav08hVo3WLdOMdvbPwUiQE1aA9EzGG2iHw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>218422429</pqid></control><display><type>article</type><title>Calcium Increase in the Mammillary Bodies with Aging</title><source>Springer Nature</source><creator>Suwannahoy, Patipath ; Tohno, Setsuko ; Mahakkanukrauh, Pasuk ; Minami, Takeshi ; Tohno, Yoshiyuki</creator><creatorcontrib>Suwannahoy, Patipath ; Tohno, Setsuko ; Mahakkanukrauh, Pasuk ; Minami, Takeshi ; Tohno, Yoshiyuki</creatorcontrib><description>To elucidate compositional changes of the mammillary body with aging, the authors investigated age-related changes of elements, relationships among their elements, and gender differences in the mammillary bodies by direct chemical analysis. After ordinary dissection at Nara Medical University was finished, the mammillary bodies were resected from the cerebra of the subjects. The subjects consisted of 19 men and 25 women, ranging in age from 70 to 101 years (average age = 83.8 ± 7.2 years). After ashing of the mammillary bodies with nitric acid and perchloric acid, element contents were determined by inductively coupled plasma-atomic emission spectrometry. It was found that the Ca content increased slightly and significantly in the mammillary bodies with aging, but the P, S, Mg, Zn, Fe, and Na contents did not change significantly with aging. Regarding the relationships among elements, significant correlations were found among the contents of Ca, P, S, and Mg in the mammillary bodies, with one exception between P and Mg contents. With regard to the seven element contents, no significant gender differences were found in the mammillary bodies.</description><identifier>ISSN: 0163-4984</identifier><identifier>EISSN: 1559-0720</identifier><identifier>DOI: 10.1007/s12011-009-8491-x</identifier><identifier>PMID: 19669711</identifier><language>eng</language><publisher>New York: New York : Humana Press Inc</publisher><subject>Aged ; Aged, 80 and over ; Aging ; Aging - physiology ; Biochemistry ; Biomedical and Life Sciences ; Biotechnology ; Calcium ; Calcium - metabolism ; Chemical analysis ; Female ; Humans ; Life Sciences ; Magnesium - metabolism ; Male ; Mammillary Bodies - metabolism ; Nitric acid ; Nitric oxide ; Nutrition ; Oncology ; Phosphorus ; Phosphorus - metabolism ; Spectrometry ; Sulfur - metabolism</subject><ispartof>Biological trace element research, 2010-06, Vol.135 (1-3), p.56-66</ispartof><rights>Humana Press Inc. 2009</rights><rights>Springer Science+Business Media, LLC 2010</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c458t-43cd50379a01dfe1073267e3cc0a431ca773481021f31ac92c81bf0f5638419a3</citedby><cites>FETCH-LOGICAL-c458t-43cd50379a01dfe1073267e3cc0a431ca773481021f31ac92c81bf0f5638419a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19669711$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Suwannahoy, Patipath</creatorcontrib><creatorcontrib>Tohno, Setsuko</creatorcontrib><creatorcontrib>Mahakkanukrauh, Pasuk</creatorcontrib><creatorcontrib>Minami, Takeshi</creatorcontrib><creatorcontrib>Tohno, Yoshiyuki</creatorcontrib><title>Calcium Increase in the Mammillary Bodies with Aging</title><title>Biological trace element research</title><addtitle>Biol Trace Elem Res</addtitle><addtitle>Biol Trace Elem Res</addtitle><description>To elucidate compositional changes of the mammillary body with aging, the authors investigated age-related changes of elements, relationships among their elements, and gender differences in the mammillary bodies by direct chemical analysis. After ordinary dissection at Nara Medical University was finished, the mammillary bodies were resected from the cerebra of the subjects. The subjects consisted of 19 men and 25 women, ranging in age from 70 to 101 years (average age = 83.8 ± 7.2 years). After ashing of the mammillary bodies with nitric acid and perchloric acid, element contents were determined by inductively coupled plasma-atomic emission spectrometry. It was found that the Ca content increased slightly and significantly in the mammillary bodies with aging, but the P, S, Mg, Zn, Fe, and Na contents did not change significantly with aging. Regarding the relationships among elements, significant correlations were found among the contents of Ca, P, S, and Mg in the mammillary bodies, with one exception between P and Mg contents. With regard to the seven element contents, no significant gender differences were found in the mammillary bodies.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aging</subject><subject>Aging - physiology</subject><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Biotechnology</subject><subject>Calcium</subject><subject>Calcium - metabolism</subject><subject>Chemical analysis</subject><subject>Female</subject><subject>Humans</subject><subject>Life Sciences</subject><subject>Magnesium - metabolism</subject><subject>Male</subject><subject>Mammillary Bodies - metabolism</subject><subject>Nitric acid</subject><subject>Nitric oxide</subject><subject>Nutrition</subject><subject>Oncology</subject><subject>Phosphorus</subject><subject>Phosphorus - metabolism</subject><subject>Spectrometry</subject><subject>Sulfur - metabolism</subject><issn>0163-4984</issn><issn>1559-0720</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNqFkU1PGzEQhi3UCkLgB3BpV71w2nbG4_XHEaKWIqXqoXC2jOMNRtldamdV-u9xtJGQOMDJBz_va888jJ0hfEUA9S0jB8QawNRaGKyfDtgMm8bUoDh8YDNASbUwWhyx45wfAFBxQ4fsCI2URiHOmFi4jY9jV133PgWXQxX7ansfql-u6-Jm49L_6nJYxZCrf3F7X12sY78-YR9bt8nhdH_O2e2P7zeLn_Xy99X14mJZe9HobS3IrxogZRzgqg0IirhUgbwHJwi9U4qERuDYEjpvuNd410LbSNICjaM5O596H9Pwdwx5a7uYfSi_6sMwZqsbqRpDHN4llZCckzDyfZLIkEKpC_nlFfkwjKkvA1uOWnAuyjLnDCfIpyHnFFr7mGJXtmYR7E6SnSTZIsnuJNmnkvm0Lx7vurB6SeytFIBPQC5X_Tqkl5ffav08hVo3WLdOMdvbPwUiQE1aA9EzGG2iHw</recordid><startdate>20100601</startdate><enddate>20100601</enddate><creator>Suwannahoy, Patipath</creator><creator>Tohno, Setsuko</creator><creator>Mahakkanukrauh, Pasuk</creator><creator>Minami, Takeshi</creator><creator>Tohno, Yoshiyuki</creator><general>New York : Humana Press Inc</general><general>Humana Press Inc</general><general>Springer Nature B.V</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QH</scope><scope>7QP</scope><scope>7TN</scope><scope>7U7</scope><scope>7UA</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BKSAR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>F1W</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H97</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>L.G</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PCBAR</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20100601</creationdate><title>Calcium Increase in the Mammillary Bodies with Aging</title><author>Suwannahoy, Patipath ; Tohno, Setsuko ; Mahakkanukrauh, Pasuk ; Minami, Takeshi ; Tohno, Yoshiyuki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c458t-43cd50379a01dfe1073267e3cc0a431ca773481021f31ac92c81bf0f5638419a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aging</topic><topic>Aging - physiology</topic><topic>Biochemistry</topic><topic>Biomedical and Life Sciences</topic><topic>Biotechnology</topic><topic>Calcium</topic><topic>Calcium - metabolism</topic><topic>Chemical analysis</topic><topic>Female</topic><topic>Humans</topic><topic>Life Sciences</topic><topic>Magnesium - metabolism</topic><topic>Male</topic><topic>Mammillary Bodies - metabolism</topic><topic>Nitric acid</topic><topic>Nitric oxide</topic><topic>Nutrition</topic><topic>Oncology</topic><topic>Phosphorus</topic><topic>Phosphorus - metabolism</topic><topic>Spectrometry</topic><topic>Sulfur - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Suwannahoy, Patipath</creatorcontrib><creatorcontrib>Tohno, Setsuko</creatorcontrib><creatorcontrib>Mahakkanukrauh, Pasuk</creatorcontrib><creatorcontrib>Minami, Takeshi</creatorcontrib><creatorcontrib>Tohno, Yoshiyuki</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Aqualine</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Oceanic Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Water Resources Abstracts</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>Earth, Atmospheric &amp; Aquatic Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Aquatic Science &amp; Fisheries Abstracts (ASFA) 3: Aquatic Pollution &amp; Environmental Quality</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Aquatic Science &amp; Fisheries Abstracts (ASFA) Professional</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>ProQuest Biological Science Journals</collection><collection>Earth, Atmospheric &amp; Aquatic Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Biological trace element research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Suwannahoy, Patipath</au><au>Tohno, Setsuko</au><au>Mahakkanukrauh, Pasuk</au><au>Minami, Takeshi</au><au>Tohno, Yoshiyuki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Calcium Increase in the Mammillary Bodies with Aging</atitle><jtitle>Biological trace element research</jtitle><stitle>Biol Trace Elem Res</stitle><addtitle>Biol Trace Elem Res</addtitle><date>2010-06-01</date><risdate>2010</risdate><volume>135</volume><issue>1-3</issue><spage>56</spage><epage>66</epage><pages>56-66</pages><issn>0163-4984</issn><eissn>1559-0720</eissn><abstract>To elucidate compositional changes of the mammillary body with aging, the authors investigated age-related changes of elements, relationships among their elements, and gender differences in the mammillary bodies by direct chemical analysis. After ordinary dissection at Nara Medical University was finished, the mammillary bodies were resected from the cerebra of the subjects. The subjects consisted of 19 men and 25 women, ranging in age from 70 to 101 years (average age = 83.8 ± 7.2 years). After ashing of the mammillary bodies with nitric acid and perchloric acid, element contents were determined by inductively coupled plasma-atomic emission spectrometry. It was found that the Ca content increased slightly and significantly in the mammillary bodies with aging, but the P, S, Mg, Zn, Fe, and Na contents did not change significantly with aging. Regarding the relationships among elements, significant correlations were found among the contents of Ca, P, S, and Mg in the mammillary bodies, with one exception between P and Mg contents. With regard to the seven element contents, no significant gender differences were found in the mammillary bodies.</abstract><cop>New York</cop><pub>New York : Humana Press Inc</pub><pmid>19669711</pmid><doi>10.1007/s12011-009-8491-x</doi><tpages>11</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0163-4984
ispartof Biological trace element research, 2010-06, Vol.135 (1-3), p.56-66
issn 0163-4984
1559-0720
language eng
recordid cdi_proquest_miscellaneous_856759320
source Springer Nature
subjects Aged
Aged, 80 and over
Aging
Aging - physiology
Biochemistry
Biomedical and Life Sciences
Biotechnology
Calcium
Calcium - metabolism
Chemical analysis
Female
Humans
Life Sciences
Magnesium - metabolism
Male
Mammillary Bodies - metabolism
Nitric acid
Nitric oxide
Nutrition
Oncology
Phosphorus
Phosphorus - metabolism
Spectrometry
Sulfur - metabolism
title Calcium Increase in the Mammillary Bodies with Aging
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T12%3A30%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Calcium%20Increase%20in%20the%20Mammillary%20Bodies%20with%20Aging&rft.jtitle=Biological%20trace%20element%20research&rft.au=Suwannahoy,%20Patipath&rft.date=2010-06-01&rft.volume=135&rft.issue=1-3&rft.spage=56&rft.epage=66&rft.pages=56-66&rft.issn=0163-4984&rft.eissn=1559-0720&rft_id=info:doi/10.1007/s12011-009-8491-x&rft_dat=%3Cproquest_cross%3E2023186271%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c458t-43cd50379a01dfe1073267e3cc0a431ca773481021f31ac92c81bf0f5638419a3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=218422429&rft_id=info:pmid/19669711&rfr_iscdi=true