Aspects of gene polymorphisms in cerebral infarction: inflammatory cytokines

During the last decade, a growing corpus of evidence has indicated an important role of inflammatory cytokines in the pathogenesis of cerebral lesion following stroke. Recent data suggest that genetics may in turn contribute to modulating the effects of inflammatory cytokines on cerebral infarction...

Full description

Saved in:
Bibliographic Details
Published in:Cellular and molecular life sciences : CMLS 2005-04, Vol.62 (7-8), p.824-833
Main Authors: Um, J-Y, Jeong, H-J, Park, R-K, Hong, S-H, Kim, H M
Format: Article
Language:English
Subjects:
Animals
Cell Adhesion Molecules - genetics
Cell Adhesion Molecules - immunology
Cerebral infarction
Cerebral Infarction - etiology
Cerebral Infarction - genetics
Cerebral Infarction - immunology
Cytokines
Cytokines - genetics
Cytokines - immunology
Genetics
Humans
Pathology
Polymorphism
Polymorphism, Genetic
Stroke
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c421t-d36c349cfb47d34ff5a85b999c03da90b4b846308522dda9eaccaaa9efe250e03
cites
container_end_page 833
container_issue 7-8
container_start_page 824
container_title Cellular and molecular life sciences : CMLS
container_volume 62
creator Um, J-Y
Jeong, H-J
Park, R-K
Hong, S-H
Kim, H M
description During the last decade, a growing corpus of evidence has indicated an important role of inflammatory cytokines in the pathogenesis of cerebral lesion following stroke. Recent data suggest that genetics may in turn contribute to modulating the effects of inflammatory cytokines on cerebral infarction (CI). This paper reviews the physiologic characteristics of major inflammatory cytokines and recent research developments related to cell biology and pathobiology in CI. In particular, this review focuses on the genetic aspects of inflammatory cytokines and their implications in CI.
doi_str_mv 10.1007/s00018-004-4267-9
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_856769957</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2044082481</sourcerecordid><originalsourceid>FETCH-LOGICAL-c421t-d36c349cfb47d34ff5a85b999c03da90b4b846308522dda9eaccaaa9efe250e03</originalsourceid><addsrcrecordid>eNqNkUtLxDAUhYMojq8f4EaKC11Vbx7Nw52ILxhwo-AupGmqHdumJp3F_HtTZkBwoa7OIXz35nAPQscYLjCAuIwAgGUOwHJGuMjVFtrDjECuQODtjeeSvM7QfoyLBBeS8F00S8olA7GH5tdxcHaMma-zN9e7bPDtqvNheG9iF7Omz6wLrgymTb42wY6N768m35quM6MPq8yuRv_R9C4eop3atNEdbfQAvdzdPt885POn-8eb63luGcFjXlFuKVO2LpmoKKvrwsiiVEpZoJVRULJSMk5BFoRU6cEZa41JWjtSgAN6gM7Xe4fgP5cujrpronVta3rnl1HLgguuVCH-R3JOaSLPfiW5EJIrgf8EsUjRCzKlPP0BLvwy9OkwmrL0LVA8BcRryAYfY3C1HkLTmbDSGPRUsl6XrFPJeipZqzRzslm8LDtXfU9sWqVfqZCiMQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>346760317</pqid></control><display><type>article</type><title>Aspects of gene polymorphisms in cerebral infarction: inflammatory cytokines</title><source>Springer Nature:Jisc Collections:Springer Nature Read and Publish 2023-2025: Springer Reading List</source><source>PubMed Central</source><creator>Um, J-Y ; Jeong, H-J ; Park, R-K ; Hong, S-H ; Kim, H M</creator><creatorcontrib>Um, J-Y ; Jeong, H-J ; Park, R-K ; Hong, S-H ; Kim, H M</creatorcontrib><description>During the last decade, a growing corpus of evidence has indicated an important role of inflammatory cytokines in the pathogenesis of cerebral lesion following stroke. Recent data suggest that genetics may in turn contribute to modulating the effects of inflammatory cytokines on cerebral infarction (CI). This paper reviews the physiologic characteristics of major inflammatory cytokines and recent research developments related to cell biology and pathobiology in CI. In particular, this review focuses on the genetic aspects of inflammatory cytokines and their implications in CI.</description><identifier>ISSN: 1420-682X</identifier><identifier>EISSN: 1420-9071</identifier><identifier>DOI: 10.1007/s00018-004-4267-9</identifier><identifier>PMID: 15868407</identifier><language>eng</language><publisher>Switzerland: Springer Nature B.V</publisher><subject>Animals ; Cell Adhesion Molecules - genetics ; Cell Adhesion Molecules - immunology ; Cerebral infarction ; Cerebral Infarction - etiology ; Cerebral Infarction - genetics ; Cerebral Infarction - immunology ; Cytokines ; Cytokines - genetics ; Cytokines - immunology ; Genetics ; Humans ; Pathology ; Polymorphism ; Polymorphism, Genetic ; Stroke</subject><ispartof>Cellular and molecular life sciences : CMLS, 2005-04, Vol.62 (7-8), p.824-833</ispartof><rights>Birkhäuser Verlag, Basel 2005</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c421t-d36c349cfb47d34ff5a85b999c03da90b4b846308522dda9eaccaaa9efe250e03</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15868407$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Um, J-Y</creatorcontrib><creatorcontrib>Jeong, H-J</creatorcontrib><creatorcontrib>Park, R-K</creatorcontrib><creatorcontrib>Hong, S-H</creatorcontrib><creatorcontrib>Kim, H M</creatorcontrib><title>Aspects of gene polymorphisms in cerebral infarction: inflammatory cytokines</title><title>Cellular and molecular life sciences : CMLS</title><addtitle>Cell Mol Life Sci</addtitle><description>During the last decade, a growing corpus of evidence has indicated an important role of inflammatory cytokines in the pathogenesis of cerebral lesion following stroke. Recent data suggest that genetics may in turn contribute to modulating the effects of inflammatory cytokines on cerebral infarction (CI). This paper reviews the physiologic characteristics of major inflammatory cytokines and recent research developments related to cell biology and pathobiology in CI. In particular, this review focuses on the genetic aspects of inflammatory cytokines and their implications in CI.</description><subject>Animals</subject><subject>Cell Adhesion Molecules - genetics</subject><subject>Cell Adhesion Molecules - immunology</subject><subject>Cerebral infarction</subject><subject>Cerebral Infarction - etiology</subject><subject>Cerebral Infarction - genetics</subject><subject>Cerebral Infarction - immunology</subject><subject>Cytokines</subject><subject>Cytokines - genetics</subject><subject>Cytokines - immunology</subject><subject>Genetics</subject><subject>Humans</subject><subject>Pathology</subject><subject>Polymorphism</subject><subject>Polymorphism, Genetic</subject><subject>Stroke</subject><issn>1420-682X</issn><issn>1420-9071</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><recordid>eNqNkUtLxDAUhYMojq8f4EaKC11Vbx7Nw52ILxhwo-AupGmqHdumJp3F_HtTZkBwoa7OIXz35nAPQscYLjCAuIwAgGUOwHJGuMjVFtrDjECuQODtjeeSvM7QfoyLBBeS8F00S8olA7GH5tdxcHaMma-zN9e7bPDtqvNheG9iF7Omz6wLrgymTb42wY6N768m35quM6MPq8yuRv_R9C4eop3atNEdbfQAvdzdPt885POn-8eb63luGcFjXlFuKVO2LpmoKKvrwsiiVEpZoJVRULJSMk5BFoRU6cEZa41JWjtSgAN6gM7Xe4fgP5cujrpronVta3rnl1HLgguuVCH-R3JOaSLPfiW5EJIrgf8EsUjRCzKlPP0BLvwy9OkwmrL0LVA8BcRryAYfY3C1HkLTmbDSGPRUsl6XrFPJeipZqzRzslm8LDtXfU9sWqVfqZCiMQ</recordid><startdate>200504</startdate><enddate>200504</enddate><creator>Um, J-Y</creator><creator>Jeong, H-J</creator><creator>Park, R-K</creator><creator>Hong, S-H</creator><creator>Kim, H M</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7QP</scope><scope>7QR</scope><scope>7SS</scope><scope>7T5</scope><scope>7T7</scope><scope>7TK</scope><scope>7TM</scope><scope>7TO</scope><scope>7U7</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7N</scope><scope>M7P</scope><scope>MBDVC</scope><scope>P64</scope><scope>PATMY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PYCSY</scope><scope>Q9U</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>200504</creationdate><title>Aspects of gene polymorphisms in cerebral infarction: inflammatory cytokines</title><author>Um, J-Y ; Jeong, H-J ; Park, R-K ; Hong, S-H ; Kim, H M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c421t-d36c349cfb47d34ff5a85b999c03da90b4b846308522dda9eaccaaa9efe250e03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Animals</topic><topic>Cell Adhesion Molecules - genetics</topic><topic>Cell Adhesion Molecules - immunology</topic><topic>Cerebral infarction</topic><topic>Cerebral Infarction - etiology</topic><topic>Cerebral Infarction - genetics</topic><topic>Cerebral Infarction - immunology</topic><topic>Cytokines</topic><topic>Cytokines - genetics</topic><topic>Cytokines - immunology</topic><topic>Genetics</topic><topic>Humans</topic><topic>Pathology</topic><topic>Polymorphism</topic><topic>Polymorphism, Genetic</topic><topic>Stroke</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Um, J-Y</creatorcontrib><creatorcontrib>Jeong, H-J</creatorcontrib><creatorcontrib>Park, R-K</creatorcontrib><creatorcontrib>Hong, S-H</creatorcontrib><creatorcontrib>Kim, H M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural &amp; Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Environmental Science Collection</collection><collection>ProQuest Central Basic</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Cellular and molecular life sciences : CMLS</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Um, J-Y</au><au>Jeong, H-J</au><au>Park, R-K</au><au>Hong, S-H</au><au>Kim, H M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Aspects of gene polymorphisms in cerebral infarction: inflammatory cytokines</atitle><jtitle>Cellular and molecular life sciences : CMLS</jtitle><addtitle>Cell Mol Life Sci</addtitle><date>2005-04</date><risdate>2005</risdate><volume>62</volume><issue>7-8</issue><spage>824</spage><epage>833</epage><pages>824-833</pages><issn>1420-682X</issn><eissn>1420-9071</eissn><abstract>During the last decade, a growing corpus of evidence has indicated an important role of inflammatory cytokines in the pathogenesis of cerebral lesion following stroke. Recent data suggest that genetics may in turn contribute to modulating the effects of inflammatory cytokines on cerebral infarction (CI). This paper reviews the physiologic characteristics of major inflammatory cytokines and recent research developments related to cell biology and pathobiology in CI. In particular, this review focuses on the genetic aspects of inflammatory cytokines and their implications in CI.</abstract><cop>Switzerland</cop><pub>Springer Nature B.V</pub><pmid>15868407</pmid><doi>10.1007/s00018-004-4267-9</doi><tpages>10</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1420-682X
ispartof Cellular and molecular life sciences : CMLS, 2005-04, Vol.62 (7-8), p.824-833
issn 1420-682X
1420-9071
language eng
recordid cdi_proquest_miscellaneous_856769957
source Springer Nature:Jisc Collections:Springer Nature Read and Publish 2023-2025: Springer Reading List; PubMed Central
subjects Animals
Cell Adhesion Molecules - genetics
Cell Adhesion Molecules - immunology
Cerebral infarction
Cerebral Infarction - etiology
Cerebral Infarction - genetics
Cerebral Infarction - immunology
Cytokines
Cytokines - genetics
Cytokines - immunology
Genetics
Humans
Pathology
Polymorphism
Polymorphism, Genetic
Stroke
title Aspects of gene polymorphisms in cerebral infarction: inflammatory cytokines
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T02%3A06%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Aspects%20of%20gene%20polymorphisms%20in%20cerebral%20infarction:%20inflammatory%20cytokines&rft.jtitle=Cellular%20and%20molecular%20life%20sciences%20:%20CMLS&rft.au=Um,%20J-Y&rft.date=2005-04&rft.volume=62&rft.issue=7-8&rft.spage=824&rft.epage=833&rft.pages=824-833&rft.issn=1420-682X&rft.eissn=1420-9071&rft_id=info:doi/10.1007/s00018-004-4267-9&rft_dat=%3Cproquest_cross%3E2044082481%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c421t-d36c349cfb47d34ff5a85b999c03da90b4b846308522dda9eaccaaa9efe250e03%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=346760317&rft_id=info:pmid/15868407&rfr_iscdi=true