Serum and Bronchoalveolar Lavage Fluid Galactomannan Assays in Patients with Pulmonary Aspergilloma

The sensitivities of the serum and bronchoalveolar lavage galactomannan (GM) assays in 48 patients with pulmonary aspergilloma were 38% (13 of 34; 95% confidence interval [CI], 22%-56%) and 92% (33 of 36; 95% CI, 78%-98%), respectively. The positivity of serum GM assays was significantly higher in p...

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Published in:Clinical infectious diseases 2011-04, Vol.52 (7), p.e149-e152
Main Authors: Park, Seong Yeon, Lee, Sang-Oh, Choi, Sang-Ho, Jeong, Jin-Yong, Sung, Heungsup, Kim, Mi-Na, Choi, Chang-Min, Hong, Sang-Bum, Oh, Yeon-Mok, Shim, Tae-Sun, Lim, Chae-Man, Koh, Younsuck, Kim, Dong Soon, Kim, Yang Soo, Woo, Jun Hee, Kim, Sung-Han
Format: Article
Language:English
Subjects:
Adult
Aged
Bronchoalveolar Lavage Fluid - chemistry
Clinical Laboratory Techniques - methods
Female
Humans
Male
Mannans - analysis
Middle Aged
Pulmonary Aspergillosis - diagnosis
Sensitivity and Specificity
Serum - chemistry
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Summary:The sensitivities of the serum and bronchoalveolar lavage galactomannan (GM) assays in 48 patients with pulmonary aspergilloma were 38% (13 of 34; 95% confidence interval [CI], 22%-56%) and 92% (33 of 36; 95% CI, 78%-98%), respectively. The positivity of serum GM assays was significantly higher in patients with hemoptysis than in those without hemoptysis (52% vs 9%; P 5 .02). The sensitivities of the serum and bronchoalveolar lavage galactomannan (GM) assays in 48 patients with pulmonary aspergilloma were 38% (13 of 34; 95% confidence interval [CI], 22%-56%) and 92% (33 of 36; 95% CI, 78%-98%), respectively. The positivity of serum GM assays was significantly higher in patients with hemoptysis than in those without hemoptysis (52% vs 9%; P = .02).
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/cir027