Environmental occurrence and reproductive effects of the pharmaceutical fluoxetine in native freshwater mussels

The present study measured the occurrence, distribution, and bioaccumulation of fluoxetine in samples of water, polar organic chemical integrative sampler (POCIS), sediment, and caged freshwater mussels at stream sites near a municipal wastewater treatment facility effluent discharge. We assessed th...

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Bibliographic Details
Published in:Environmental toxicology and chemistry 2010-06, Vol.29 (6), p.1311-1318
Main Authors: Bringolf, Robert B., Heltsley, Rebecca M., Newton, Teresa J., Eads, Chris B., Fraley, Stephen J., Shea, Damian, Cope, W. Gregory
Format: Article
Language:English
Subjects:
Animals
Behavior
Bioaccumulation
Bivalvia - drug effects
Bivalvia - growth & development
Channels
Effluents
Elliptio complanata
Female
Females
Fluoxetine - analysis
Fluoxetine - pharmacokinetics
Fluoxetine - toxicity
Freshwater
Freshwaters
Glochidia
Laboratory tests
Lampsilis cardium
Lampsilis fasciola
Larvae
Male
Mollusks
Municipal wastewater
Mussels
Pharmaceutical
Pharmaceuticals
Prozac
Reproduction
Reproduction - drug effects
Sediments
Studies
Tissue Distribution
Tissues
Toxicology
Unionidae
Wastewater discharges
Wastewater treatment
Water analysis
Water Pollutants, Chemical - analysis
Water Pollutants, Chemical - pharmacokinetics
Water Pollutants, Chemical - toxicity
Water sampling
Water treatment
Water treatment plants
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Summary:The present study measured the occurrence, distribution, and bioaccumulation of fluoxetine in samples of water, polar organic chemical integrative sampler (POCIS), sediment, and caged freshwater mussels at stream sites near a municipal wastewater treatment facility effluent discharge. We assessed the relation of the environmental concentrations to reproductive endpoints in mussels in acute laboratory tests. Concentrations of fluoxetine in water and POCIS samples were similar (
ISSN:0730-7268
1552-8618
1552-8618
DOI:10.1002/etc.157