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Breast lesions in patients with Mazabraud or McCune-Albright syndrome

Mazabraud syndrome is a very rare condition with ap- proximately 67 cases documented in the international literature.1 It is associated with monostotic or polyostotic forms of fibrous dysplasia and soft tissue or, more often, intramuscular myxomas arising from benign proliferation of dysplastic fibr...

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Published in:The American surgeon 2011-01, Vol.77 (1), p.E7-8
Main Authors: Michalopoulos, Nikolaos V, Tsamis, Dimitrios, Linardoutsos, Dimitrios, Flessas, Ioannis, Zagouri, Flora, Liakou, Paraskevi, Filippakis, George M, Zografos, George C
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container_title The American surgeon
container_volume 77
creator Michalopoulos, Nikolaos V
Tsamis, Dimitrios
Linardoutsos, Dimitrios
Flessas, Ioannis
Zagouri, Flora
Liakou, Paraskevi
Filippakis, George M
Zografos, George C
description Mazabraud syndrome is a very rare condition with ap- proximately 67 cases documented in the international literature.1 It is associated with monostotic or polyostotic forms of fibrous dysplasia and soft tissue or, more often, intramuscular myxomas arising from benign proliferation of dysplastic fibrous connective tissue and proliferation of cells with mesenchymatic origin. A recent review listed until now 68 patients with this syndrome.1 Breast disorders have been reported in two of these cases and included a breast fibrosarcoma in a 23-year-old female patient with multiple myxomas and polyostotic fibrous dysplasia and a breast fibrous dysplasia in a 35-year-old woman with multiple myx- omas, polyostotic fibrous dysplasia as well as "cafe au lait'' skin spots.3, 4 The breast lesion identified in the patient of the current report proved to be a benign in- tracystic ductal papilloma.
doi_str_mv 10.1177/000313481107700105
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source Sage Journals Online
subjects Adult
Biopsy, Needle
Breast Cyst - diagnosis
Breast Cyst - pathology
Breast Cyst - surgery
Female
Fibrous Dysplasia, Polyostotic - diagnosis
Fibrous Dysplasia, Polyostotic - pathology
Fibrous Dysplasia, Polyostotic - surgery
Follow-Up Studies
Humans
Immunohistochemistry
Magnetic Resonance Imaging - methods
Mammaplasty - methods
Mastectomy - methods
Mutation
Patients
Proteins
Risk Assessment
Severity of Illness Index
Treatment Outcome
Ultrasonography, Doppler - methods
title Breast lesions in patients with Mazabraud or McCune-Albright syndrome
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