SPORADIC FUNDIC GLAND POLYP‐RELATED ADENOMAS OCCURRED IN NON‐ATROPHIC GASTRIC MUCOSA WITHOUT HELICOBACTER PYLORI INFECTION

We report three cases of adenoma associated with sporadic fundic gland polyp (FGP) in the non‐atrophic fundic gland mucosa without Helicobacter pylori (HP) infection, which was verified with both serological and histopathological examinations. Gastric tubular adenoma (flat adenoma) is common and foc...

Full description

Saved in:
Bibliographic Details
Published in:Digestive endoscopy 2011-04, Vol.23 (2), p.182-186
Main Authors: Tazaki, Shuhei, Nozu, Fumihiko, Yosikawa, Nozomi, Imawari, Michio, Suzuki, Naoto, Tominaga, Kouji, Hoshino, Mitsunori, Suzuki, Satoshi, Hayashi, Kazuhiko
Format: Article
Language:English
Subjects:
adenoma
Adenoma - pathology
Adenoma - surgery
Adult
Biomarkers, Tumor - analysis
Female
Gastric Fundus - pathology
Gastric Mucosa - pathology
Gastritis, Atrophic - pathology
Gastroscopy
Helicobacter Infections - pathology
Helicobacter pylori
Humans
Middle Aged
Polyps - pathology
Polyps - surgery
sporadic fundic gland polyp
Stomach Neoplasms - pathology
Stomach Neoplasms - surgery
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We report three cases of adenoma associated with sporadic fundic gland polyp (FGP) in the non‐atrophic fundic gland mucosa without Helicobacter pylori (HP) infection, which was verified with both serological and histopathological examinations. Gastric tubular adenoma (flat adenoma) is common and focal cancers occurring in the hyperplastic polyp of foveolar cell type are also sometimes experienced. However, adenomas occurring in sporadic FGP are valuable, as they are very rare, in upper gastrointestinal endoscopy. Whether or not these adenoma lesions of three sporadic FGP cases may become the background of protruded gastric cancers without HP infection remains unclear. Therefore, we emphasize the importance of histological examination on fundic gland polyps that are >5 mm in size to accumulate new similar cases. Follow‐up studies of these lesions are also needed to evaluate their outcomes.
ISSN:0915-5635
1443-1661
DOI:10.1111/j.1443-1661.2010.01082.x