Adhesion of Preosteoblasts and Fibroblasts onto Poly(pentafluorostyrene)-Based Glycopolymeric Films and their Biocompatibility

An efficient and metal‐catalyst free method of glycopolymer synthesis via thiol/para‐fluorine “click” reaction was used to graft acetylated 1‐thio‐β‐D‐glucopyranose and 1‐thio‐β‐D‐galactopyranose onto a homopolymer of pentafluorostyrene (PFS) as well as onto a block copolymer of styrene and PFS. Sub...

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Bibliographic Details
Published in:Macromolecular bioscience 2011-04, Vol.11 (4), p.535-548
Main Authors: Babiuch, Krzysztof, Becer, C. Remzi, Gottschaldt, Michael, Delaney, Joseph T., Weisser, Jürgen, Beer, Birgitt, Wyrwa, Ralf, Schnabelrauch, Matthias, Schubert, Ulrich S.
Format: Article
Language:English
Subjects:
3T3 Cells
adhesion
Animals
Applied sciences
Cell Adhesion
Chemical modifications
Chemical reactions and properties
click reaction
Coated Materials, Biocompatible - chemistry
coatings
coatings, functionalization of polymers
Exact sciences and technology
Fibroblasts - cytology
Fluorocarbon Polymers - chemical synthesis
Fluorocarbon Polymers - chemistry
functionalization of polymers
glycopolymer
Materials Testing - methods
Mice
Organic polymers
Physicochemistry of polymers
Polystyrenes - chemical synthesis
Polystyrenes - chemistry
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Summary:An efficient and metal‐catalyst free method of glycopolymer synthesis via thiol/para‐fluorine “click” reaction was used to graft acetylated 1‐thio‐β‐D‐glucopyranose and 1‐thio‐β‐D‐galactopyranose onto a homopolymer of pentafluorostyrene (PFS) as well as onto a block copolymer of styrene and PFS. Subsequent deprotection of the carbohydrate moieties yielded well‐defined, sugar‐modified polymers (PDI 
ISSN:1616-5187
1616-5195
DOI:10.1002/mabi.201000374