Genetic improvement of grass pea for low neurotoxin (β-ODAP) content

Grass pea is a promising crop for adaptation under climate change because of its tolerance to drought, water-logging and salinity, and being almost free from insect-pests and diseases. In spite of such virtues, global area under its cultivation has decreased because of ban on its cultivation in many...

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Bibliographic Details
Published in:Food and chemical toxicology 2011-03, Vol.49 (3), p.589-600
Main Authors: Kumar, Shiv, Bejiga, G., Ahmed, S., Nakkoul, H., Sarker, A.
Format: Article
Language:English
Subjects:
Amino Acids, Diamino - poisoning
Bangladesh
Breeding
climate change
cross pollination
cultivars
Detoxification
drought tolerance
Ethiopia
flooded conditions
genetic improvement
genetic variation
Germplasm
heirloom varieties
Humans
India
insect pests
Lathyrism - chemically induced
Lathyrus - genetics
Lathyrus - poisoning
Lathyrus sativus
Mutation
nervous system diseases
Neurotoxin
neurotoxins
Neurotoxins - poisoning
ODAP
planting date
Plants, Genetically Modified - genetics
Plants, Genetically Modified - poisoning
risk
salinity
seedlings
Seedlings - genetics
Seedlings - metabolism
seeds
soaking
Soil - chemistry
soil treatment
toxicology
Varieties
zinc sulfate
Zinc Sulfate - analysis
Zinc sulphate
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Summary:Grass pea is a promising crop for adaptation under climate change because of its tolerance to drought, water-logging and salinity, and being almost free from insect-pests and diseases. In spite of such virtues, global area under its cultivation has decreased because of ban on its cultivation in many countries. The ban is imposed due to its association with neurolathyrism, a non-reversible neurological disorder in humans and animals due to presence of neurotoxin, β-N-oxalyl- l-α,β-diaminopropionic acid (β-ODAP) in its seedlings and seeds. The traditional varieties of grass pea contain 0.5–2.5% β-ODAP. Exploitable genetic variability for β-ODAP has been observed for development of low ODAP varieties, which along with improved agronomic and detoxification practices can help reduce the risk of lathyrism. Collaborative efforts between ICARDA and NARS have resulted in development of improved varieties such as Wasie in Ethiopia, Ratan, Prateek and Mahateora in India, and BARI Khesari-1 and BARI Khesari-2 in Bangladesh with
ISSN:0278-6915
1873-6351
DOI:10.1016/j.fct.2010.06.051