Effect of 10-week long resistance training program on the acute levels of cytokines

• Published in: Journal of exercise physiology online 2010-06, Vol.13 (3), p.40-48
• Main Authors: Nunes, Joao Elias Dias, De Agostini, Guilherme Gularte, Nicioli, Cristiane, Ferreira, Fabiano Candido, Baldissera, Vilmar, Perez, Sergio Eduardo De Andrade
• Format: Article
• Language: English
• Subjects: Acute effects; Cytokines; Physiological aspects; Physiological research; Weight training; Women's fitness
• ISSN: 1097-9751; 1097-9751

Nunes JED, De Agostini GG, Nicioli C, Ferreira FC, Baldissera V, Perez SEA. Resistance Training Program and Cytokines Before and After the Completion of a Fatigue Test. JEPonline 2010; 13(3):40-48. Evidence suggests that exercise can induce the production of cytokines. We evaluated the effect of a 10-week circuit resistance training program (CRTP) on the acute effect of two fatigue tests (FT), the bench press (BP) and the leg press at 45° (LP), on the plasma concentrations of IL-6, IL-8, IL-10, IL-1 p, and TNF✓. Volunteers took two FT, which were performed in three series with 50% of 1-RM done until exhaustion and 1-minute intervals between the series, before and after the CRTP. A total of 14 non-trained women, at 39.8 ± 3.9 years, 60.6 ± 6.6 kg and 163.6 ± 6.6 cm, participated in the study. The plasma concentrations of IL-8 for the LP exercise, taken before and after the FT and from the pre- and post-training periods, were (Pre: 4.4 ± 2.6 and 5.7 ± 1.0 pg/ml, p = 0,333) and (Post: 6.4 ± 1.3 and 6.5 ± 2.1 pg/ml, p = 0,797), respectively. For the BP exercise, the levels were (Pre: 3.7 ± 3.9 and 9.0 ± 2.6 pg/ml, p = 0,057) and (Post: 5.7 ± 2.1 and 7.1 ± 2.3 pg/ml, p = 0,164). IL-6, IL-10, IL-1β, and TNF✓ did not reach the minimum limit of detection. Our data, then, support the idea that the two FT done do not provoke stress sufficient to alter the cytokinaemia. Key Words: Immune Function, Fatigue, Bench Press, Leg Press, Women.