A Three-Dimensional Bioprinting System for Use With a Hydrogel-Based Biomaterial and Printing Parameter Characterization

Bioprinting is an emerging technology for constructing tissue or bioartificial organs with complex three‐dimensional (3D) structures. It provides high‐precision spatial shape forming ability on a larger scale than conventional tissue engineering methods, and simultaneous multiple components composit...

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Bibliographic Details
Published in:Artificial organs 2010-11, Vol.34 (11), p.1044-1048
Main Authors: Song, Seung-Joon, Choi, Jaesoon, Park, Yong-Doo, Lee, Jung-Joo, Hong, So Young, Sun, Kyung
Format: Article
Language:English
Subjects:
3D printing
Bioartificial organ
Bioartificial Organs
Biocompatible Materials
Bioprinting
Computer-Aided Design
Equipment Design
Hyaluronic Acid
Hydrogels
Regenerative medicine
Tissue engineering
Tissue Engineering - methods
Tissue Scaffolds
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Summary:Bioprinting is an emerging technology for constructing tissue or bioartificial organs with complex three‐dimensional (3D) structures. It provides high‐precision spatial shape forming ability on a larger scale than conventional tissue engineering methods, and simultaneous multiple components composition ability. Bioprinting utilizes a computer‐controlled 3D printer mechanism for 3D biological structure construction. To implement minimal pattern width in a hydrogel‐based bioprinting system, a study on printing characteristics was performed by varying printer control parameters. The experimental results showed that printing pattern width depends on associated printer control parameters such as printing flow rate, nozzle diameter, and nozzle velocity. The system under development showed acceptable feasibility of potential use for accurate printing pattern implementation in tissue engineering applications and is another example of novel techniques for regenerative medicine based on computer‐aided biofabrication system.
ISSN:0160-564X
1525-1594
DOI:10.1111/j.1525-1594.2010.01143.x