Environmental enrichment delays pup-induced maternal behavior in rats

• Published in: Developmental psychobiology 2011-05, Vol.53 (4), p.371-382
• Main Authors: Mann, Phyllis E., Gervais, Kristen J.
• Format: Article
• Language: English
• Subjects: Analysis of Variance; Animals; Anxiety; Behavior, Animal - physiology; Corticosterone; Corticosterone - blood; Data processing; elevated plus maze; Enrichment; Environment; Environmental changes; environmental enrichment; Female; Housing; Maternal behavior; Maternal Behavior - physiology; nulliparous; Postpartum; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Stress; Stress, Physiological - physiology; Stress, Psychological - blood; Time Factors; virgin
• ISSN: 0012-1630; 1098-2302; 1098-2302
• DOI: 10.1002/dev.20526

Adult, virgin rats do not spontaneously display maternal behavior when exposed to foster pups. However, continuous daily exposure of the female to foster pups for about 5–7 days can induce a set of maternal behaviors similar to those shown by postpartum dams. Induction latencies depend upon a number of factors, including the stress and anxiety levels of the female. The goal of this study was to attempt to mitigate the likely stressfulness of being singly housed during testing by enriching the rat's home cage environment and to determine if the concomitant environmental change would alter the latency to express maternal behavior. In addition, the effect of varying the number of test pups used for testing was examined. Two groups of virgin Sprague–Dawley rats were first tested on the elevated plus maze after 1 week of exposure to either control (standard housing) or enriched conditions. One week later, maternal behavior testing began using one or three pups. Upon completion of maternal behavior testing, plasma corticosterone concentrations were determined following a mild stressor. The data indicate that enrichment tends to increase anxiety‐like behaviors in the elevated plus maze. In addition, enrichment delayed the onset of maternal behavior irrespective of the number of test pups. There were no effects of environmental enrichment on plasma corticosterone levels following exposure to a stressor. These results indicate that what is considered a modestly enriched environment delays the expression of pup‐oriented responses and does not apparently reduce stress or improve performance on all behavioral tasks. © 2011 Wiley Periodicals, Inc. Dev Psychobiol 53:371–382, 2011.