Elevated risk of papillary thyroid cancer in Korean patients with Hashimoto's thyroiditis

Background. Hashimoto's thyroiditis (HT) and higher levels of thyroid‐stimulating hormone (TSH) have been proposed as risk factors for papillary thyroid cancer (PTC), but this issue is still being debated. The purpose of this study was whether HT was related to the risk of PTC over TSH. Methods...

Full description

Saved in:
Bibliographic Details
Published in:Head & neck 2011-05, Vol.33 (5), p.691-695
Main Authors: Kim, Kyung Won, Park, Young Joo, Kim, Eun Hye, Park, So Yeon, Park, Do Joong, Ahn, Soon-Hyun, Park, Do Joon, Jang, Hak C., Cho, Bo Youn
Format: Article
Language:English
Subjects:
Adenocarcinoma, Follicular - epidemiology
Adenocarcinoma, Follicular - pathology
Adenocarcinoma, Follicular - surgery
Autoantibodies - blood
Biological and medical sciences
Carcinoma, Papillary - epidemiology
Carcinoma, Papillary - pathology
Carcinoma, Papillary - surgery
Endocrinopathies
Female
Hashimoto Disease - epidemiology
Hashimoto's thyroiditis
Humans
Iodide Peroxidase - immunology
Male
Malignant tumors
Medical sciences
Middle Aged
Multivariate Analysis
Non tumoral diseases. Target tissue resistance. Benign neoplasms
Otorhinolaryngology. Stomatology
papillary thyroid cancer
Republic of Korea - epidemiology
Risk Factors
Sex Factors
Thyroglobulin - immunology
thyroid cancer
Thyroid Neoplasms - epidemiology
Thyroid Neoplasms - pathology
Thyroid Neoplasms - surgery
Thyroid Nodule - epidemiology
Thyroid Nodule - surgery
thyroid-stimulating hormone
Thyroid. Thyroid axis (diseases)
Thyroidectomy
thyrotropin
Thyrotropin - blood
Thyroxine - blood
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background. Hashimoto's thyroiditis (HT) and higher levels of thyroid‐stimulating hormone (TSH) have been proposed as risk factors for papillary thyroid cancer (PTC), but this issue is still being debated. The purpose of this study was whether HT was related to the risk of PTC over TSH. Methods. We enrolled 1329 patients (1028 with PTC, 52 with follicular thyroid cancer, and 249 with benign disease) of 1490 patients who underwent thyroidectomy. Results. The TSH concentration was not different among patients with PTC or benign disease. Our study showed that men (odds ratio [OR] = 1.54; p = .049) and the presence of HT (OR = 2.96; p
ISSN:1043-3074
1097-0347
DOI:10.1002/hed.21518