Acral persistent papular mucinosis: a case report and literature review

Summary Acral persistent papular mucinosis is a rare subtype of localized lichen myxedematosus. It shows symmetric, asymptomatic, chronic, ivory to flesh‐colored, 2–5 mm sized papules arranged on the dorsa of the hands and extensor aspects of the distal forearms. Thirty‐two cases including two from...

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Published in:Journal der Deutschen Dermatologischen Gesellschaft 2011-05, Vol.9 (5), p.354-359
Main Authors: Luo, Di-Qing, Wu, Liang-Cai, Liu, Jun-Hua, Zhang, Hai-Yan
Format: Article
Language:English
Subjects:
acral persistent papular mucinosis
Adult
Electrocoagulation - methods
Female
Hand Dermatoses - surgery
Humans
localized lichen myxedematosus
Mucinoses - surgery
treatment
Treatment Outcome
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Summary:Summary Acral persistent papular mucinosis is a rare subtype of localized lichen myxedematosus. It shows symmetric, asymptomatic, chronic, ivory to flesh‐colored, 2–5 mm sized papules arranged on the dorsa of the hands and extensor aspects of the distal forearms. Thirty‐two cases including two from China, appear to fit the proposed diagnostic criteria. We report a 31‐year‐old Chinese woman who presented with papules on the extensor aspects of her hands and distal forearms. Histopathology revealed a circumscribed area in the upper and mid reticular dermis with splaying of collagen fibers caused by amorphous deposits. The material was mucin, as it stained positively with alcian blue at pH 2.5. The thyroid profile was normal, and there was no evidence for lupus erythematous. The lesions were treated with electrofulguration and resolved leaving mild scars; there has been no recurrence at follow‐up after one year. We also review the literature on this rare form of mucinosis.
ISSN:1610-0379
1610-0387
DOI:10.1111/j.1610-0387.2010.07594.x