Comparison of In Vivo Assessment of Vulnerable Plaque by 64-Slice Multislice Computed Tomography Versus Optical Coherence Tomography

• Published in: The American journal of cardiology 2011-05, Vol.107 (9), p.1270-1277
• Main Authors: Ito, Tsuyoshi, MD, Terashima, Mitsuyasu, MD, Kaneda, Hideaki, MD, Nasu, Kenya, MD, Matsuo, Hitoshi, MD, Ehara, Mariko, MD, Kinoshita, Yoshihisa, MD, Kimura, Masashi, MD, Tanaka, Nobuyoshi, MD, Habara, Maoto, MD, Katoh, Osamu, MD, Suzuki, Takahiko, MD
• Format: Article
• Language: English
• Subjects: Aged; Biological and medical sciences; Cardiology. Vascular system; Cardiovascular; Cardiovascular disease; Comparative analysis; Confidence intervals; Correlation analysis; Female; Humans; Male; Medical sciences; Middle Aged; Plaque, Atherosclerotic - diagnosis; Plaque, Atherosclerotic - diagnostic imaging; Studies; Tomography; Tomography, Optical Coherence; Tomography, X-Ray Computed
• ISSN: 0002-9149; 1879-1913
• DOI: 10.1016/j.amjcard.2010.12.036

The aim of this study was to investigate the possibility of 64-slice multislice computed tomography (MSCT) to detect vulnerable plaque derived by optical coherence tomography. From September 2007 through December 2009, 122 lesions in 81 patients were evaluated by 64-slice MSCT and optical coherence tomography. Based on optical coherence tomographic findings, lesions were classified as thin-capped fibroatheroma (TCFA; n = 37) and non-TCFA (n = 85). Mean computed tomographic density value of the lesion was lower and remodeling index was larger in the TCFA group (44.9 ± 19.2 vs 78.7 ± 25.0 HU, p