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Phytochemistry and larvicidal activity of Eucalyptus camaldulensis against malaria vector,Anopheles stephensi

<正>Objective:To determine phytochemistry and larvicidal activity of Eucalyptus eamaldulensis against Anopheles stephensi.Methods:The chemical compositions of the leaf essential oils were analyzed using gas chromatography/mass spectrometry(GC/MS).The larvicidal activity of essential oil...

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Published in:Asian Pacific journal of tropical medicine 2010-11, Vol.3 (11), p.841-845
Main Authors: Medhi, Sedaghat Mohamad, Reza, SaneiAli, Mahnaz, Khnavi, Reza, Abai Mohammad, Abbas, Hadjiakhoondi, Fatemeh, Mohtarami, Hassan, Vatandoost
Format: Article
Language:English
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Summary:<正>Objective:To determine phytochemistry and larvicidal activity of Eucalyptus eamaldulensis against Anopheles stephensi.Methods:The chemical compositions of the leaf essential oils were analyzed using gas chromatography/mass spectrometry(GC/MS).The larvicidal activity of essential oils and extract of leaf were tested against 4th instar larvae of laboratory-reared Anopheles stephensi.Results:GC/MS analyses identified the presence of 28 compounds corresponding to 99.60%of the total oil.The main constituents in the leaf essential oil were 1,8-cineole(69.46%),γ-Terpinene(15.10%),α-Pinene(5.47%) and Globulol(2%).The leaf extract and volatile oil exerted significant larvicidal activity with LC50 values of 89.85 and 397.75 ppm,respectively.Clear dose-response relationships were established with the highest dose of 320 ppm essential oil extract resulted almost 100%mortality in the population.Conclusions:The larvicidal properties suggest that the essential oil of plant is a potential source of valuable larvicidal compounds against malaria vector and can be used as an alternative to synthetic insecticides.
ISSN:1995-7645
2352-4146
DOI:10.1016/S1995-7645(10)60203-9