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The role of adenosine monophosphate kinase in remodeling white adipose tissue metabolism

Recent evidence indicates that the enzyme adenosine monophosphate (AMP) kinase exerts important fat-reducing effects in the adipose tissue, which has created great interest in this enzyme as a potential target for obesity treatment. This review summarizes our findings that chronic AMP kinase activat...

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Published in:	Exercise and sport sciences reviews 2011-04, Vol.39 (2), p.102-108
Main Authors:	Gaidhu, Mandeep Pinky, Ceddia, Rolando Bacis
Format:	Article
Language:	English
Subjects:	Adenosine Kinase - metabolism Adenosine Monophosphate - metabolism Adipose Tissue, White - metabolism Animals Energy Metabolism - physiology Enzyme Activation Glucose - metabolism Lipid Metabolism - physiology Obesity - metabolism Phosphotransferases - metabolism
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description	Recent evidence indicates that the enzyme adenosine monophosphate (AMP) kinase exerts important fat-reducing effects in the adipose tissue, which has created great interest in this enzyme as a potential target for obesity treatment. This review summarizes our findings that chronic AMP kinase activation remodels adipocyte glucose and lipid metabolism and enhances the ability of adipose tissue to dissipate energy within itself and reduce adiposity.
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subjects	Adenosine Kinase - metabolism Adenosine Monophosphate - metabolism Adipose Tissue, White - metabolism Animals Energy Metabolism - physiology Enzyme Activation Glucose - metabolism Lipid Metabolism - physiology Obesity - metabolism Phosphotransferases - metabolism
title	The role of adenosine monophosphate kinase in remodeling white adipose tissue metabolism
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