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Anaesthetic and postanaesthetic effect of isoflurane on the multiple-unit activity of the immature rat hippocampus
We investigated anesthetic and postanaesthetic effect of isoflurane on the multi-unit activity (MUA) in the CA3 region of immature rat hippocampus. MUA amplitude did not significantly change during application of isoflurane. On the other hand MUA frequency significantly decreased during the anesthes...
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| Published in: | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) Ukraine : 1994), 2011, Vol.57 (1), p.17-20 |
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| Main Authors: | , |
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| Language: | English |
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| container_end_page | 20 |
| container_issue | 1 |
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| container_title | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) |
| container_volume | 57 |
| creator | Isaeva, E V Isaev, D S |
| description | We investigated anesthetic and postanaesthetic effect of isoflurane on the multi-unit activity (MUA) in the CA3 region of immature rat hippocampus. MUA amplitude did not significantly change during application of isoflurane. On the other hand MUA frequency significantly decreased during the anesthesia. After isoflurane discontinuation two phases of MUA frequency recovery were observed: initial rapid increase followed by a slower recovery to the control level. Comparison of recovering period of the receptor mediated systems and spontaneous field activity from isoflurane anesthesia is discussed. |
| doi_str_mv | 10.15407/fz57.01.017 |
| format | article |
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Bogomoletz Institute of Physiology National Acad-emy of Sciences of Ukraine, Kyiv, Ukraine</creatorcontrib><title>Anaesthetic and postanaesthetic effect of isoflurane on the multiple-unit activity of the immature rat hippocampus</title><title>Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)</title><addtitle>Fiziol Zh</addtitle><description>We investigated anesthetic and postanaesthetic effect of isoflurane on the multi-unit activity (MUA) in the CA3 region of immature rat hippocampus. MUA amplitude did not significantly change during application of isoflurane. On the other hand MUA frequency significantly decreased during the anesthesia. After isoflurane discontinuation two phases of MUA frequency recovery were observed: initial rapid increase followed by a slower recovery to the control level. Comparison of recovering period of the receptor mediated systems and spontaneous field activity from isoflurane anesthesia is discussed.</description><subject>Action Potentials - drug effects</subject><subject>Action Potentials - physiology</subject><subject>Anesthesia</subject><subject>Anesthetics, Inhalation - administration & dosage</subject><subject>Anesthetics, Inhalation - pharmacology</subject><subject>Animals</subject><subject>CA3 Region, Hippocampal - drug effects</subject><subject>CA3 Region, Hippocampal - growth & development</subject><subject>CA3 Region, Hippocampal - physiology</subject><subject>In Vitro Techniques</subject><subject>Isoflurane - administration & dosage</subject><subject>Isoflurane - pharmacology</subject><subject>Pyramidal Cells - drug effects</subject><subject>Pyramidal Cells - physiology</subject><subject>Rats</subject><subject>Rats, Sprague-Dawley</subject><subject>Time Factors</subject><subject>Volatilization</subject><issn>2522-9028</issn><issn>2522-9036</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNpNkEtLAzEUhYMottTuXEt2bpyax2RmsizFFxTc6HrI5EEDM5MxD6H-elOtRbhwL_d8HDgHgGuMVpiVqL43X6xeIZynPgNzwggpOKLV-ekmzQwsQ7AdYqRCFWX1JZgRzDAlhMyBX49Ch7jT0UooRgUnF6L499PGaBmhM9AGZ_rkxaihG2GW4ZD6aKdeF2m0EQoZ7aeN-wN7UO0wiJi8hl5EuLPT5KQYphSuwIURfdDL416A98eHt81zsX19etmst4UkCNWFJlJSgjStGOtKLCRulFGSaCw6JDvKNVOiJEZyybmqZN0pwXmDjEI5XifpAtz--k7efaQcqB1skLrvcwKXQttUtKSYM57Ju19SeheC16advB2E37cYtT89t4eeW4Tz1Bm_ORqnbtDqBP-1Sr8BHA57kg</recordid><startdate>2011</startdate><enddate>2011</enddate><creator>Isaeva, E V</creator><creator>Isaev, D S</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2011</creationdate><title>Anaesthetic and postanaesthetic effect of isoflurane on the multiple-unit activity of the immature rat hippocampus</title><author>Isaeva, E V ; Isaev, D S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2007-e2cc320e3655b41ac18dfdc2e1ab0cb39e5da42fc9c99d6c7bda9980fd0215bc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Action Potentials - drug effects</topic><topic>Action Potentials - physiology</topic><topic>Anesthesia</topic><topic>Anesthetics, Inhalation - administration & dosage</topic><topic>Anesthetics, Inhalation - pharmacology</topic><topic>Animals</topic><topic>CA3 Region, Hippocampal - drug effects</topic><topic>CA3 Region, Hippocampal - growth & development</topic><topic>CA3 Region, Hippocampal - physiology</topic><topic>In Vitro Techniques</topic><topic>Isoflurane - administration & dosage</topic><topic>Isoflurane - pharmacology</topic><topic>Pyramidal Cells - drug effects</topic><topic>Pyramidal Cells - physiology</topic><topic>Rats</topic><topic>Rats, Sprague-Dawley</topic><topic>Time Factors</topic><topic>Volatilization</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Isaeva, E V</creatorcontrib><creatorcontrib>Isaev, D S</creatorcontrib><creatorcontrib>O.O. Bogomoletz Institute of Physiology National Acad-emy of Sciences of Ukraine, Kyiv, Ukraine</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Isaeva, E V</au><au>Isaev, D S</au><aucorp>O.O. 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| ispartof | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2011, Vol.57 (1), p.17-20 |
| issn | 2522-9028 2522-9036 |
| language | eng |
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| source | ROAD: Directory of Open Access Scholarly Resources |
| subjects | Action Potentials - drug effects Action Potentials - physiology Anesthesia Anesthetics, Inhalation - administration & dosage Anesthetics, Inhalation - pharmacology Animals CA3 Region, Hippocampal - drug effects CA3 Region, Hippocampal - growth & development CA3 Region, Hippocampal - physiology In Vitro Techniques Isoflurane - administration & dosage Isoflurane - pharmacology Pyramidal Cells - drug effects Pyramidal Cells - physiology Rats Rats, Sprague-Dawley Time Factors Volatilization |
| title | Anaesthetic and postanaesthetic effect of isoflurane on the multiple-unit activity of the immature rat hippocampus |
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