Two cases of fungemia due to Candida lusitaniae and a literature review

Reported here are two cases of candidemia caused by Candida lusitaniae that occurred in two immunocompromised patients at Hospital Universitario "La Fe" in Valencia, Spain. Case 1 involved a low-birth-weight premature infant with congenital nephrotic syndrome who was successfully treated w...

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Bibliographic Details
Published in:European journal of clinical microbiology & infectious diseases 2002-04, Vol.21 (4), p.294-299
Main Authors: VIUDES, A, PEMAN, J, CANTON, E, SALAVERT, M, UBEDA, P, LOPEZ-RIBOT, J. L, GOBERNADO, M
Format: Article
Language:English
Subjects:
Amphotericin B - therapeutic use
Antifungal Agents - therapeutic use
Biological and medical sciences
Candida - isolation & purification
Candida lusitaniae
Female
Fungemia - drug therapy
Fungemia - microbiology
Human mycoses
Humans
Infant, Newborn
Infectious diseases
Literature reviews
Lymphoma
Medical sciences
Middle Aged
Mycoses
Mycotic sepsis
Opportunistic Infections - drug therapy
Opportunistic Infections - microbiology
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Summary:Reported here are two cases of candidemia caused by Candida lusitaniae that occurred in two immunocompromised patients at Hospital Universitario "La Fe" in Valencia, Spain. Case 1 involved a low-birth-weight premature infant with congenital nephrotic syndrome who was successfully treated with amphotericin B, and case 2 involved a 50-year old woman with a high-grade malignancy lymphoma who succumbed to the infection. Antifungal susceptibility testing of the Candida lusitaniae isolates recovered from both patients revealed sensitivity to amphotericin, 5-flucytosine and fluconazole. Results are presented and discussed together with a comprehensive review of the literature, covering all previously reported cases of fungemia caused by this emerging pathogen.
ISSN:0934-9723
1435-4373
DOI:10.1007/s10096-002-0713-5