Haematological complications in otherwise healthy children hospitalized for varicella

Abstract Although varicella is commonly regarded as a mild childhood disease, complications may occur and frequently require hospitalization. The aim of this study was to establish the type and frequency of varicella complications among hospitalized paediatric patients over a 4.5-year period. This a...

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Bibliographic Details
Published in:Vaccine 2011-02, Vol.29 (8), p.1534-1537
Main Authors: Elena, Bozzola, Anna, Quondamcarlo, Andrzej, Krzysztofiak, Elisabetta, Pandolfi, Laura, Lancella, Alberto, Tozzi
Format: Article
Language:English
Subjects:
Adolescent
Age
Allergy and Immunology
Anemia
Antibodies, Viral - blood
Applied microbiology
Bacterial infections
Biological and medical sciences
Blood platelets
Chickenpox - complications
Chickenpox - epidemiology
Child
Child, Hospitalized
Child, Preschool
Children
Disease
Female
Fundamental and applied biological sciences. Psychology
Hematologic Diseases - complications
Hematologic Diseases - epidemiology
Hematologic Diseases - virology
Hematology
Hospitalization
Hospitals
Human viral diseases
Humans
Immunization
Infant
Infant, Newborn
Infections
Infectious diseases
Italy - epidemiology
Male
Medical sciences
Microbiology
Mortality
Nervous System Diseases - complications
Nervous System Diseases - epidemiology
Nervous System Diseases - virology
Skin
Studies
Vaccines
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
Varicella
Varicella complication
Varicella vaccination
Viral diseases
Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye
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Description
Summary:Abstract Although varicella is commonly regarded as a mild childhood disease, complications may occur and frequently require hospitalization. The aim of this study was to establish the type and frequency of varicella complications among hospitalized paediatric patients over a 4.5-year period. This analysis included the medical charts of 306 patients admitted to the Infectious Disease Unit, Children Hospital Bambino Gesù, Roma, Italy from 2006 to 2010 for varicella disease. The most common complications were haematological disorders (41.5%) followed by neurological ones (23.5%). Varicella vaccination in childhood immunization program must be increased.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2010.12.095