Genetic composition of six miniSTR in a Brazilian Mulatto sample population

Abstract The present study characterizes the genetic variability of Mulatto population based on the polymorphism of six miniSTR autosomal loci, known as Non Codis 01 and 02 (NC01 and NC02) and evaluate their applicability in forensic genetics. A sample of 102 unrelated Brazilian mulattoes were genot...

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Bibliographic Details
Published in:Journal of forensic and legal medicine 2011-05, Vol.18 (4), p.184-186
Main Authors: Aranda, Xavier G, Lage, Caroline A.C, Planz, John V, Eisenberg, Arthur J, Moura-Neto, Rodrigo S, Silva, Rosane
Format: Article
Language:English
Subjects:
Admixture
Brazil
DNA Fingerprinting
Ethnic Groups - genetics
Forensic medicine
Gene Frequency
Genetic Variation
Genetics
Genetics, Population
Genotype
Genotype & phenotype
Humans
Microsatellite Repeats
NCO 1
NCO 2
Non CODIS
Pathology
Polymorphism
Studies
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Summary:Abstract The present study characterizes the genetic variability of Mulatto population based on the polymorphism of six miniSTR autosomal loci, known as Non Codis 01 and 02 (NC01 and NC02) and evaluate their applicability in forensic genetics. A sample of 102 unrelated Brazilian mulattoes were genotyped for miniSTR loci D1S1677, D2S441, D4S2364 (miniplex NC02) and 45 individuals for D10S1248, D14S1434, D22S1045 (miniplex NC01). No significant deviations from Hardy–Weinberg equilibrium expectations were detected. The combined power of discrimination (PD) and mean power of exclusion (PE) were 0.999996 and 0.98991, respectively. The results also support the effectiveness of the NC01and NC02 miniplexes for human identification.
ISSN:1752-928X
1878-7487
DOI:10.1016/j.jflm.2011.02.003