Prognostic value of absence or presence of coronary artery disease determined by 64-slice computed tomography coronary angiography A systematic review and meta-analysis

To determine via a meta-analysis the prognostic value of 64-slice computed tomography angiography (CTA) by quantifying risk of major adverse cardiac events (MACE) in different patient groups classified according to CT angiographic findings. A systematic literature search and meta-analyses was conduc...

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Bibliographic Details
Published in:International Journal of Cardiovascular Imaging 2011-03, Vol.27 (3), p.413-420
Main Authors: Abdulla, Jawdat, Asferg, Camilla, Kofoed, Klaus Fuglsang
Format: Article
Language:English
Subjects:
Aged
Angiography
Cardiac Imaging
Cardiology
Computed tomography
Coronary Angiography - methods
Coronary Stenosis - complications
Coronary Stenosis - diagnostic imaging
Coronary Stenosis - mortality
Coronary Stenosis - therapy
Evidence-Based Medicine
Female
Heart
Heart diseases
Humans
Imaging
Male
Medicine
Medicine & Public Health
Middle Aged
Myocardial infarction
Myocardial Infarction - diagnostic imaging
Myocardial Infarction - etiology
Myocardial Infarction - mortality
Myocardial Infarction - therapy
Myocardial Revascularization
Odds Ratio
Predictive Value of Tests
Prognosis
Radiology
Review
Reviews
Risk Assessment
Risk Factors
Risk groups
Severity of Illness Index
Stenosis
Tomography, X-Ray Computed
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Description
Summary:To determine via a meta-analysis the prognostic value of 64-slice computed tomography angiography (CTA) by quantifying risk of major adverse cardiac events (MACE) in different patient groups classified according to CT angiographic findings. A systematic literature search and meta-analyses was conducted on 10 studies examining stable, symptomatic and intermediate risk patients by 64-slice CTA. Patients were followed up for a mean of 21 month. Patient groups with CT-angiographic non-obstructive (stenosis 0.05 for heterogeneity. 64-slice CTA is able to differentiate low-risk from high-risk patients with suspected or known CAD. Absence of CAD predicts excellent prognosis, while obstructive CAD is associated with markedly increased risk of MACE.
ISSN:1569-5794
1573-0743
1875-8312
DOI:10.1007/s10554-010-9652-x