Long-term effects of propolis on serum biochemical parameters of rainbow trout (Oncorhynchus mykiss)

• Published in: Ecotoxicology and environmental safety 2011-03, Vol.74 (3), p.315-318
• Main Authors: Beyraghdar Kashkooli, Omid, Ebrahimi Dorcheh, Eisa, Mahboobi-Soofiani, Nasrollah, Samie, Abdolhossein
• Format: Article
• Language: English
• Subjects: adverse effects; Alanine Transaminase - blood; albumins; alkaline phosphatase; Alkaline Phosphatase - blood; Animal, plant and microbial ecology; Animals; Anti-Infective Agents - administration & dosage; Anti-Infective Agents - toxicity; Applied ecology; Aspartate Aminotransferases - blood; Biochemistry; Biological and medical sciences; Biomarkers - blood; Biomarkers - metabolism; Cholesterol; Cholesterol, HDL - blood; Cholesterol, LDL - blood; diet; Diets; Dose-Response Relationship, Drug; Ecotoxicology, biological effects of pollution; Environmental Exposure - analysis; fish feeding; Fundamental and applied biological sciences. Psychology; General aspects; globulins; high density lipoprotein; L-Lactate Dehydrogenase - blood; lactate dehydrogenase; Lipoproteins; Long-term effects; low density lipoprotein; Oncorhynchus mykiss; Oncorhynchus mykiss - blood; Propolis; Propolis - administration & dosage; Propolis - toxicity; Rainbow trout; Serum Albumin - metabolism; Serum biochemistry; Serum Globulins - metabolism; Serums; Side effects; Toxicity; triacylglycerols; Triglycerides - blood; Trout; Water Pollutants, Chemical - administration & dosage; Water Pollutants, Chemical - toxicity
• ISSN: 0147-6513; 1090-2414
• DOI: 10.1016/j.ecoenv.2010.10.014

Long-term effects of propolis administration on serum biochemical parameters of rainbow trout (Oncorhynchus mykiss) were investigated. To determine the possible toxicity and side effects of propolis, fish were fed on diets containing 0, 0.5, 1.5, 4.5 and 9g propolis/kg diet for 8 weeks. At the end of the experiment, various seric biochemical parameters were determined. Our results showed that all dosages induced no significant alterations in growth parameters and the seric levels of total protein, albumin, globulin, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides and activities of glutamic pyruvic transaminase, glutamic oxaloacetic transaminase, alkaline phosphatase and lactate dehydrogenase, when compared to the control group. On the basis of our findings, propolis is a non-toxic substance for rainbow trout and its long-term administration might not have any side effects.