A Multicenter Analysis of "Time to Microcatheter" for Endovascular Therapy in Acute Ischemic Stroke

ABSTRACT PURPOSE At present, no time recommendation for initiation of endovascular treatment in acute ischemic stroke is available. A multicenter analysis was designed to identify variables that prolong “time to microcatheter,” defined as the time interval from computed tomographic scan to microcath...

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Bibliographic Details
Published in:Journal of neuroimaging 2011-04, Vol.21 (2), p.159-164
Main Authors: Miley, Jefferson T., Memon, Muhammad Zeeshan, Hussein, Haitham M., Valenta, Douglas A., Suri, M. Fareed K., Vazquez, Gabriela, Qureshi, Adnan I.
Format: Article
Language:English
Subjects:
acute ischemic stroke
Aged
Analysis of Variance
Catheterization - methods
Cerebral Angiography
Comorbidity
Contrast Media - administration & dosage
endovascular
Female
Fibrinolytic Agents - therapeutic use
Humans
Intraarterial thrombolysis
Male
Patient Selection
Stroke - diagnostic imaging
Stroke - drug therapy
stroke performance
Thrombolytic Therapy - methods
Time Factors
time to microcatheter
Tissue Plasminogen Activator - therapeutic use
Tomography, X-Ray Computed
Treatment Outcome
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Summary:ABSTRACT PURPOSE At present, no time recommendation for initiation of endovascular treatment in acute ischemic stroke is available. A multicenter analysis was designed to identify variables that prolong “time to microcatheter,” defined as the time interval from computed tomographic scan to microcatheter placement in the cerebral circulation. METHODS Consecutive acute ischemic stroke patients from 3 academic stroke centers were included. Analysis of covariance was used to evaluate different variables that prolong “time to microcatheter.” RESULTS Ninety‐one patients underwent emergent endovascular treatment for acute ischemic stroke. Mean “time to microcatheter” was 174 ± 60 minutes. No significant time difference was found in patients who were intubated, presented at night or weekends, were administered intravenous recombinant tissue plasminogen activator, or underwent additional imaging prior to endovascular treatment. “Time to microcatheter” was significantly longer in nonlevel I trauma centers and in patients with National Institutes of Health Stroke Scale Score of 10 to 19. CONCLUSION Wide variability of “time to microcatheter” among institutions highlights the need for standardized time goals.
ISSN:1051-2284
1552-6569
DOI:10.1111/j.1552-6569.2009.00432.x