Study of a new group of bioregulators isolated from the greater plantain (Plantago major L.)

Proteins with physicochemical properties and biological activity similar to those of membranotropic homeostatic tissue-specific bioregulators that had been found earlier in various animal tissues were discovered in leaves of the common plantain (Plantago major L.). To study the specific activity of...

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Bibliographic Details
Published in:Applied biochemistry and microbiology 2011-03, Vol.47 (2), p.128-135
Main Authors: Krasnov, M. S, Yamskova, V. P, Margasyuk, D. V, Kulikova, O. G, Il'ina, A. P, Rybakova, E. Yu, Yamskov, I. A
Format: Article
Language:English
Subjects:
Animal tissues
Biochemistry
Biomedical and Life Sciences
Biotechnology
Cell adhesion & migration
Life Sciences
Medical Microbiology
Microbiology
Physicochemical properties
Plant biology
Plantago major
Pleurodeles waltl
Proteins
Salamandridae
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Summary:Proteins with physicochemical properties and biological activity similar to those of membranotropic homeostatic tissue-specific bioregulators that had been found earlier in various animal tissues were discovered in leaves of the common plantain (Plantago major L.). To study the specific activity of these plant proteins, we developed an experimental model for organotypic roller cultivation of newt (Pleurodeles waltl) skin tissue in vitro. We showed that the plant proteins of interest exert the wound-healing effect, which is characteristic of this plant, on the skin of vertebrates both in vitro and in vivo.
ISSN:0003-6838
1608-3024
DOI:10.1134/S0003683811020086