Cardio-Ankle Vascular Index Could Reflect Plaque Burden in the Coronary Artery

Cardio-ankle vascular index (CAVI) using the volume plethysmographic method is a noninvasive atherosclerotic indicator which is not influenced by blood pressure. Coronary intravascular ultrasound (IVUS) is a reliable technique to measure progression of atherosclerosis. The association between CAVI a...

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Bibliographic Details
Published in:Angiology 2011-07, Vol.62 (5), p.401-408
Main Authors: Horinaka, Shigeo, Yabe, Akihisa, Yagi, Hiroshi, Ishimura, Kimihiko, Hara, Hitoshi, Iemura, Tomomi, Ishimitsu, Toshihiko
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Ankle - blood supply
Aortic Valve - physiopathology
Biological and medical sciences
Blood and lymphatic vessels
Blood Flow Velocity - physiology
Cardiology. Vascular system
Cohort Studies
Coronary Artery Disease - diagnosis
Coronary Artery Disease - etiology
Coronary Artery Disease - physiopathology
Coronary heart disease
Coronary Stenosis - diagnosis
Coronary Stenosis - etiology
Coronary Stenosis - physiopathology
Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
Female
Heart
Humans
Male
Medical sciences
Middle Aged
Plaque, Atherosclerotic - diagnosis
Plaque, Atherosclerotic - etiology
Plaque, Atherosclerotic - physiopathology
Plethysmography
Predictive Value of Tests
Reproducibility of Results
Retrospective Studies
Ultrasonography, Interventional
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Summary:Cardio-ankle vascular index (CAVI) using the volume plethysmographic method is a noninvasive atherosclerotic indicator which is not influenced by blood pressure. Coronary intravascular ultrasound (IVUS) is a reliable technique to measure progression of atherosclerosis. The association between CAVI and IVUS has not been reported. The aim of this study was to evaluate the association between CAVI and the plaque burden measured by IVUS in the left main coronary artery (LMCA) in patients with coronary heart disease and normal LMCA. Cardio-ankle vascular index was significantly correlated with percentage plaque area (r = .649, P < .0001) measured by IVUS in the most diseased segment of LMCA. Cardio-ankle vascular index remained significant among cardiovascular disease risk factors included in the multiple regression analysis predicting percentage plaque area. Cardio-ankle vascular index was a good atherosclerotic indicator and associated with the plaque burden in nonculprit and angiographically normal LMCA.
ISSN:0003-3197
1940-1574
DOI:10.1177/0003319710395561