Dosimetric Monitoring of Nonuniform Exposure

In case of remote and contact radiation therapy of oncological diseases using photon radiation, organs and tissues around the pathological lesion (irradiation target) are exposed to nonuniform ionizing radiation. The dose–effect ratio of nonuniform ionizing radiation in the exposed organ can vary by...

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Bibliographic Details
Published in:Biomedical engineering 2011, Vol.44 (5), p.176-179
Main Authors: Lebedev, A. L., Plautin, O. N.
Format: Article
Language:English
Subjects:
Biomaterials
Biomedical engineering
Biomedical Engineering and Bioengineering
Engineering
Estimating techniques
Exposure
Ionizing radiation
Nuclear radiation
Oncology
Radiation damage
Radiation dosage
Radiation therapy
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Description
Summary:In case of remote and contact radiation therapy of oncological diseases using photon radiation, organs and tissues around the pathological lesion (irradiation target) are exposed to nonuniform ionizing radiation. The dose–effect ratio of nonuniform ionizing radiation in the exposed organ can vary by dozens of times. Therefore, it is difficult to estimate the dose of nonuniform radiation, which increases at the expense of application of different methods of exposure. In radiobiological practice, it is well known that the degree of body damage depends on the dose of radiation and exposed volume (number of exposed cells). The problem of estimation of the dose of radiation in case of nonuniform exposure can be solved by using the modal dose (dosimetric test characterizing irradiation of the maximum number of cells). This method provides a separate estimation of the degree for each method of beam therapy.
ISSN:0006-3398
1573-8256
DOI:10.1007/s10527-011-9181-5