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2D spatially controlled polymer micro patterning for cellular behavior studies
A simple and effective method to functionalize glass surfaces that enable polymer micropatterning and subsequent spatially controlled adhesion of cells is reported in this paper. The method involves the application of laser induced forward transfer (LIFT) to achieve polymer patterning in a single st...
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Published in: | Applied surface science 2011-04, Vol.257 (12), p.5250-5254 |
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container_end_page | 5254 |
container_issue | 12 |
container_start_page | 5250 |
container_title | Applied surface science |
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creator | Dinca, V. Palla-Papavlu, A. Paraico, I. Lippert, T. Wokaun, A. Dinescu, M. |
description | A simple and effective method to functionalize glass surfaces that enable polymer micropatterning and subsequent spatially controlled adhesion of cells is reported in this paper. The method involves the application of laser induced forward transfer (LIFT) to achieve polymer patterning in a single step onto cell repellent substrates (i.e. polyethyleneglycol (PEG)). This approach was used to produce micron-size polyethyleneimine (PEI)-patterns alternating with cell-repellent areas. The focus of this work is the ability of SH-SY5Y human neuroblastoma cells to orient, migrate, and produce organized cellular arrangements on laser generated PEI patterns. |
doi_str_mv | 10.1016/j.apsusc.2010.09.113 |
format | article |
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subjects | Adhesion Cellular Condensed matter: electronic structure, electrical, magnetic, and optical properties Condensed matter: structure, mechanical and thermal properties Cross-disciplinary physics: materials science rheology Exact sciences and technology Human Lasers Lift Micropatterning Neuronal cells Patterning Patterns Physics Polyetherimides Polyethyleneglycol Polyethyleneimine |
title | 2D spatially controlled polymer micro patterning for cellular behavior studies |
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