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2D spatially controlled polymer micro patterning for cellular behavior studies

A simple and effective method to functionalize glass surfaces that enable polymer micropatterning and subsequent spatially controlled adhesion of cells is reported in this paper. The method involves the application of laser induced forward transfer (LIFT) to achieve polymer patterning in a single st...

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Published in:Applied surface science 2011-04, Vol.257 (12), p.5250-5254
Main Authors: Dinca, V., Palla-Papavlu, A., Paraico, I., Lippert, T., Wokaun, A., Dinescu, M.
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Language:English
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cited_by cdi_FETCH-LOGICAL-c368t-9c010f13220c9bb45c51a92fccf6a3ddc1d2af053961ef78afb3849218c397673
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container_issue 12
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container_title Applied surface science
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creator Dinca, V.
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description A simple and effective method to functionalize glass surfaces that enable polymer micropatterning and subsequent spatially controlled adhesion of cells is reported in this paper. The method involves the application of laser induced forward transfer (LIFT) to achieve polymer patterning in a single step onto cell repellent substrates (i.e. polyethyleneglycol (PEG)). This approach was used to produce micron-size polyethyleneimine (PEI)-patterns alternating with cell-repellent areas. The focus of this work is the ability of SH-SY5Y human neuroblastoma cells to orient, migrate, and produce organized cellular arrangements on laser generated PEI patterns.
doi_str_mv 10.1016/j.apsusc.2010.09.113
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identifier ISSN: 0169-4332
ispartof Applied surface science, 2011-04, Vol.257 (12), p.5250-5254
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source Elsevier
subjects Adhesion
Cellular
Condensed matter: electronic structure, electrical, magnetic, and optical properties
Condensed matter: structure, mechanical and thermal properties
Cross-disciplinary physics: materials science
rheology
Exact sciences and technology
Human
Lasers
Lift
Micropatterning
Neuronal cells
Patterning
Patterns
Physics
Polyetherimides
Polyethyleneglycol
Polyethyleneimine
title 2D spatially controlled polymer micro patterning for cellular behavior studies
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