PhyloPro: a web-based tool for the generation and visualization of phylogenetic profiles across Eukarya

With increasing numbers of eukaryotic genome sequences, phylogenetic profiles of eukaryotic genes are becoming increasingly informative. Here, we introduce a new web-tool Phylopro (http://compsysbio.org/phylopro/), which uses the 120 available eukaryotic genome sequences to visualize the evolutionar...

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Bibliographic Details
Published in:Bioinformatics 2011-03, Vol.27 (6), p.877-878
Main Authors: XUEJIAN XIONG, HONGYAN SONG, TUAN ON, LOCHOVSKY, Lucas, PROVART, Nicholas J, PARKINSON, John
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biological Evolution
Cluster Analysis
Computational Biology - methods
Eukaryota - classification
Eukaryota - genetics
Fundamental and applied biological sciences. Psychology
General aspects
Genomics - methods
Internet
Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects)
Phylogeny
Programming Languages
User-Computer Interface
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Summary:With increasing numbers of eukaryotic genome sequences, phylogenetic profiles of eukaryotic genes are becoming increasingly informative. Here, we introduce a new web-tool Phylopro (http://compsysbio.org/phylopro/), which uses the 120 available eukaryotic genome sequences to visualize the evolutionary trajectories of user-defined subsets of model organism genes. Applied to pathways or complexes, PhyloPro allows the user to rapidly identify core conserved elements of biological processes together with those that may represent lineage-specific innovations. PhyloPro thus provides a valuable resource for the evolutionary and comparative studies of biological systems.
ISSN:1367-4803
1367-4811
1460-2059
DOI:10.1093/bioinformatics/btr023