Recent advances in analytical and bioanalysis applications of noble metal nanorods

In the last decade the use of anisotropic nanoparticles in analytical and bioanalytical applications has increased substantially. In particular, noble metal nanorods have unique optical properties that have attracted the interest of many research groups. The localized surface plasmon resonance (LSPR...

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Bibliographic Details
Published in:Analytical and bioanalytical chemistry 2010-11, Vol.398 (6), p.2451-2469
Main Authors: Mannelli, Ilaria, Marco, M.-Pilar
Format: Article
Language:English
Subjects:
(Bio)analytical applications
Analysis
Analytical Chemistry
Anisotropy
Binding
Biochemistry
Biosensing Techniques - instrumentation
Biosensing Techniques - methods
Characterization and Evaluation of Materials
Chemistry
Chemistry and Materials Science
Chemistry Techniques, Analytical - instrumentation
Chemistry Techniques, Analytical - methods
Equipment Design
Food Science
Gold - chemistry
Gold nanorod
Laboratory Medicine
Mathematical analysis
Monitoring/Environmental Analysis
Nanoparticles
Nanorod functionalization
Nanorods
Nanotubes - chemistry
Noble metals
Optical properties
Plasmons
Review
Surface Properties
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Summary:In the last decade the use of anisotropic nanoparticles in analytical and bioanalytical applications has increased substantially. In particular, noble metal nanorods have unique optical properties that have attracted the interest of many research groups. The localized surface plasmon resonance (LSPR) generated by interaction of light at a specific wavelength with noble metal nanoparticles was found to depend on particle size and shape and on the constituting material and the surrounding dielectric solution. Because of their anisotropic shape, nanorods are characterized by two LSPR peaks: the transverse, fixed at approximately 530 nm, and the longitudinal, which is in the visible-near infra-red region of the spectrum and varies with nanorod aspect ratio. The intense surface plasmon band enables nanorods to absorb and scatter light in the visible and near infra-red regions, and fluorescence and two-photon induced luminescence are also observed. These optical properties, with the reactivity towards binding events that induce changes in the refractive index of the surrounding solution, make nanorods a useful tool for tracking binding events in different applications, for example assembly, biosensing, in-vivo targeting and imaging, and single-molecule detection by surface-enhanced Raman spectroscopy. This review presents the promising strategies proposed for functionalizing gold nanorods and their successful use in a variety of analytical and biomedical applications.
ISSN:1618-2642
1618-2650
DOI:10.1007/s00216-010-3937-8