The use of poly-lactic acid to improve projection of reconstructed nipple

Abstract Purpose Nipple-areola reconstruction represents an important step for final mammary reconstruction. Many techniques have been described. The drawback is the progressive nipple projection loss with time from 50% to over 70% of the initial projection. In this report, we evaluated the effect o...

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Bibliographic Details
Published in:Breast (Edinburgh) 2011-06, Vol.20 (3), p.220-224
Main Authors: Dessy, L.A, Troccola, A, Ranno, R.L.M, Maruccia, M, Alfano, C, Onesti, M.G
Format: Article
Language:English
Subjects:
Absorbable Implants
Adult
Breast reconstruction
Drug Administration Schedule
Female
Hematology, Oncology and Palliative Medicine
Humans
Injections, Subcutaneous
Lactic Acid
Mammaplasty - methods
Middle Aged
Nipple reconstruction
Nipples - surgery
Poly-lactic acid
Polyesters
Polymers
Prospective Studies
Surgical Flaps
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Summary:Abstract Purpose Nipple-areola reconstruction represents an important step for final mammary reconstruction. Many techniques have been described. The drawback is the progressive nipple projection loss with time from 50% to over 70% of the initial projection. In this report, we evaluated the effect of injectable poly-lactic acid (PLLA) to improve projection of reconstructed nipples. Results We selected 12 patients with a residual nipple projection between 0.1 and 2 mm. The patients were injected locally inside the nipple with 0.5 ml of PLLA (dilution 1:4) every 4 weeks for 4 times. At the study end, patients were satisfied with results. No adverse effects were observed. After one year, an increase of nipple projection ranging from 0.5 to 3.5 mm was obtained with an average increase of 2.3 mm (282%) and this variation was statistically significant ( p  
ISSN:0960-9776
1532-3080
DOI:10.1016/j.breast.2010.11.010