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Acupuncture for pain relief during induced labour in nulliparae: a randomised controlled study
Please cite this paper as: MacKenzie I, Xu J, Cusick C, Midwinter‐Morten H, Meacher H, Mollison J, Brock M. Acupuncture for pain relief during induced labour in nulliparae: a randomised controlled study. BJOG 2011;118:440–447. Objective To assess the role of acupuncture for analgesia during labour....
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Published in: | BJOG : an international journal of obstetrics and gynaecology 2011-03, Vol.118 (4), p.440-447 |
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container_end_page | 447 |
container_issue | 4 |
container_start_page | 440 |
container_title | BJOG : an international journal of obstetrics and gynaecology |
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creator | MacKenzie, IZ Xu, J Cusick, C Midwinter‐Morten, H Meacher, H Mollison, J Brock, M |
description | Please cite this paper as: MacKenzie I, Xu J, Cusick C, Midwinter‐Morten H, Meacher H, Mollison J, Brock M. Acupuncture for pain relief during induced labour in nulliparae: a randomised controlled study. BJOG 2011;118:440–447.
Objective To assess the role of acupuncture for analgesia during labour.
Design Double‐blind study of manual, electro and sham acupuncture, and single‐blind study comparing acupuncture with a control group for analgesia for labour induction.
Setting A major obstetric unit in the UK.
Population A cohort of 105 nulliparae undergoing labour induction at term.
Methods Twenty‐three subjects needed to be randomised to each group to have an 80% power of detecting a 50% relative reduction in epidural rate with an alpha value of 0.05.
Main outcome measures The primary end point was the rate of intrapartum epidural analgesia, and the secondary end points were parenteral analgesia requirement, labour length, delivery mode, neonatal condition and postpartum haemorrhage.
Results There was no difference in epidural analgesia between acupuncture and sham acupuncture, relative risk 1.18 (95% CI 0.8–1.74), or between acupuncture and control, relative risk 0.88 (95% CI 0.66–1.19). There were no significant differences in the secondary end points between the acupuncture groups and the control group. Side effects or complications of acupuncture were not identified.
Conclusions Using the protocols studied, there was no analgesic benefit with acupuncture for pain relief during induced labour in nulliparae. |
doi_str_mv | 10.1111/j.1471-0528.2010.02825.x |
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Objective To assess the role of acupuncture for analgesia during labour.
Design Double‐blind study of manual, electro and sham acupuncture, and single‐blind study comparing acupuncture with a control group for analgesia for labour induction.
Setting A major obstetric unit in the UK.
Population A cohort of 105 nulliparae undergoing labour induction at term.
Methods Twenty‐three subjects needed to be randomised to each group to have an 80% power of detecting a 50% relative reduction in epidural rate with an alpha value of 0.05.
Main outcome measures The primary end point was the rate of intrapartum epidural analgesia, and the secondary end points were parenteral analgesia requirement, labour length, delivery mode, neonatal condition and postpartum haemorrhage.
Results There was no difference in epidural analgesia between acupuncture and sham acupuncture, relative risk 1.18 (95% CI 0.8–1.74), or between acupuncture and control, relative risk 0.88 (95% CI 0.66–1.19). There were no significant differences in the secondary end points between the acupuncture groups and the control group. Side effects or complications of acupuncture were not identified.
Conclusions Using the protocols studied, there was no analgesic benefit with acupuncture for pain relief during induced labour in nulliparae.</description><identifier>ISSN: 1470-0328</identifier><identifier>EISSN: 1471-0528</identifier><identifier>DOI: 10.1111/j.1471-0528.2010.02825.x</identifier><identifier>PMID: 21244615</identifier><identifier>CODEN: BIOGFQ</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Acupuncture ; Acupuncture Analgesia - methods ; Adult ; Analgesia, Obstetrical - methods ; Biological and medical sciences ; Childbirth & labor ; Clinical trials ; Double-Blind Method ; epidural ; Female ; Gynecology. Andrology. Obstetrics ; Humans ; induced labour ; Labor Pain - pathology ; Labor, Induced - methods ; labour outcome ; Medical sciences ; nulliparae ; Pain management ; Parity ; Pregnancy ; Treatment Outcome</subject><ispartof>BJOG : an international journal of obstetrics and gynaecology, 2011-03, Vol.118 (4), p.440-447</ispartof><rights>2011 The Authors Journal compilation © RCOG 2011 BJOG An International Journal of Obstetrics and Gynaecology</rights><rights>2015 INIST-CNRS</rights><rights>2011 The Authors Journal compilation © RCOG 2011 BJOG An International Journal of Obstetrics and Gynaecology.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4085-f34b75b165f1043903a58c5d12c65c59eba55228e44c542d7d2fdf930bcc3e1a3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23833933$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21244615$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MacKenzie, IZ</creatorcontrib><creatorcontrib>Xu, J</creatorcontrib><creatorcontrib>Cusick, C</creatorcontrib><creatorcontrib>Midwinter‐Morten, H</creatorcontrib><creatorcontrib>Meacher, H</creatorcontrib><creatorcontrib>Mollison, J</creatorcontrib><creatorcontrib>Brock, M</creatorcontrib><title>Acupuncture for pain relief during induced labour in nulliparae: a randomised controlled study</title><title>BJOG : an international journal of obstetrics and gynaecology</title><addtitle>BJOG</addtitle><description>Please cite this paper as: MacKenzie I, Xu J, Cusick C, Midwinter‐Morten H, Meacher H, Mollison J, Brock M. Acupuncture for pain relief during induced labour in nulliparae: a randomised controlled study. BJOG 2011;118:440–447.
Objective To assess the role of acupuncture for analgesia during labour.
Design Double‐blind study of manual, electro and sham acupuncture, and single‐blind study comparing acupuncture with a control group for analgesia for labour induction.
Setting A major obstetric unit in the UK.
Population A cohort of 105 nulliparae undergoing labour induction at term.
Methods Twenty‐three subjects needed to be randomised to each group to have an 80% power of detecting a 50% relative reduction in epidural rate with an alpha value of 0.05.
Main outcome measures The primary end point was the rate of intrapartum epidural analgesia, and the secondary end points were parenteral analgesia requirement, labour length, delivery mode, neonatal condition and postpartum haemorrhage.
Results There was no difference in epidural analgesia between acupuncture and sham acupuncture, relative risk 1.18 (95% CI 0.8–1.74), or between acupuncture and control, relative risk 0.88 (95% CI 0.66–1.19). There were no significant differences in the secondary end points between the acupuncture groups and the control group. Side effects or complications of acupuncture were not identified.
Conclusions Using the protocols studied, there was no analgesic benefit with acupuncture for pain relief during induced labour in nulliparae.</description><subject>Acupuncture</subject><subject>Acupuncture Analgesia - methods</subject><subject>Adult</subject><subject>Analgesia, Obstetrical - methods</subject><subject>Biological and medical sciences</subject><subject>Childbirth & labor</subject><subject>Clinical trials</subject><subject>Double-Blind Method</subject><subject>epidural</subject><subject>Female</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>induced labour</subject><subject>Labor Pain - pathology</subject><subject>Labor, Induced - methods</subject><subject>labour outcome</subject><subject>Medical sciences</subject><subject>nulliparae</subject><subject>Pain management</subject><subject>Parity</subject><subject>Pregnancy</subject><subject>Treatment Outcome</subject><issn>1470-0328</issn><issn>1471-0528</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNqFkUtLJDEUhYM4-P4LEgSZVfXkWZUSXLTiYwbBzbg1pJKUpEmnyqSD9r-flLYKbiab3OR-HO49BwCI0QyX82sxw6zBFeJEzAgqv4gIwmevW2Dvs7H9VqMKUSJ2wX5KC4RwTRDdAbsEE8ZqzPfA41znMQe9ytHCfohwVC7AaL2zPTQ5uvAEXTBZWwO96oYcyxOG7L0bVVT2DCoYVTDD0qWC6CGs4uB9KdMqm_Uh-NErn-zR5j4AD9dXfy9vq7v7m9-X87tKMyR41VPWNbzDNe8xYrRFVHGhucFE11zz1naKc0KEZUxzRkxjSG_6lqJOa2qxogfg57vuGIfnbNNKlnm09V4FO-QkRVN0G9Li_5O8uFaTuinkyTdyUdYPZY0CIYEaxmiBjjdQ7pbWyDG6pYpr-eFwAU43gEpa-b6YpV364qigtKWT0Pk79-K8XX_2MZJT4nIhp2DlFKycEpdvictXefHnfqroP8xVnVQ</recordid><startdate>201103</startdate><enddate>201103</enddate><creator>MacKenzie, IZ</creator><creator>Xu, J</creator><creator>Cusick, C</creator><creator>Midwinter‐Morten, H</creator><creator>Meacher, H</creator><creator>Mollison, J</creator><creator>Brock, M</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><general>Wiley Subscription Services, Inc</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7QP</scope><scope>ASE</scope><scope>FPQ</scope><scope>K6X</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201103</creationdate><title>Acupuncture for pain relief during induced labour in nulliparae: a randomised controlled study</title><author>MacKenzie, IZ ; Xu, J ; Cusick, C ; Midwinter‐Morten, H ; Meacher, H ; Mollison, J ; Brock, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4085-f34b75b165f1043903a58c5d12c65c59eba55228e44c542d7d2fdf930bcc3e1a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Acupuncture</topic><topic>Acupuncture Analgesia - methods</topic><topic>Adult</topic><topic>Analgesia, Obstetrical - methods</topic><topic>Biological and medical sciences</topic><topic>Childbirth & labor</topic><topic>Clinical trials</topic><topic>Double-Blind Method</topic><topic>epidural</topic><topic>Female</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>induced labour</topic><topic>Labor Pain - pathology</topic><topic>Labor, Induced - methods</topic><topic>labour outcome</topic><topic>Medical sciences</topic><topic>nulliparae</topic><topic>Pain management</topic><topic>Parity</topic><topic>Pregnancy</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MacKenzie, IZ</creatorcontrib><creatorcontrib>Xu, J</creatorcontrib><creatorcontrib>Cusick, C</creatorcontrib><creatorcontrib>Midwinter‐Morten, H</creatorcontrib><creatorcontrib>Meacher, H</creatorcontrib><creatorcontrib>Mollison, J</creatorcontrib><creatorcontrib>Brock, M</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>British Nursing Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>BJOG : an international journal of obstetrics and gynaecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MacKenzie, IZ</au><au>Xu, J</au><au>Cusick, C</au><au>Midwinter‐Morten, H</au><au>Meacher, H</au><au>Mollison, J</au><au>Brock, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Acupuncture for pain relief during induced labour in nulliparae: a randomised controlled study</atitle><jtitle>BJOG : an international journal of obstetrics and gynaecology</jtitle><addtitle>BJOG</addtitle><date>2011-03</date><risdate>2011</risdate><volume>118</volume><issue>4</issue><spage>440</spage><epage>447</epage><pages>440-447</pages><issn>1470-0328</issn><eissn>1471-0528</eissn><coden>BIOGFQ</coden><abstract>Please cite this paper as: MacKenzie I, Xu J, Cusick C, Midwinter‐Morten H, Meacher H, Mollison J, Brock M. Acupuncture for pain relief during induced labour in nulliparae: a randomised controlled study. BJOG 2011;118:440–447.
Objective To assess the role of acupuncture for analgesia during labour.
Design Double‐blind study of manual, electro and sham acupuncture, and single‐blind study comparing acupuncture with a control group for analgesia for labour induction.
Setting A major obstetric unit in the UK.
Population A cohort of 105 nulliparae undergoing labour induction at term.
Methods Twenty‐three subjects needed to be randomised to each group to have an 80% power of detecting a 50% relative reduction in epidural rate with an alpha value of 0.05.
Main outcome measures The primary end point was the rate of intrapartum epidural analgesia, and the secondary end points were parenteral analgesia requirement, labour length, delivery mode, neonatal condition and postpartum haemorrhage.
Results There was no difference in epidural analgesia between acupuncture and sham acupuncture, relative risk 1.18 (95% CI 0.8–1.74), or between acupuncture and control, relative risk 0.88 (95% CI 0.66–1.19). There were no significant differences in the secondary end points between the acupuncture groups and the control group. Side effects or complications of acupuncture were not identified.
Conclusions Using the protocols studied, there was no analgesic benefit with acupuncture for pain relief during induced labour in nulliparae.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>21244615</pmid><doi>10.1111/j.1471-0528.2010.02825.x</doi><tpages>8</tpages></addata></record> |
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subjects | Acupuncture Acupuncture Analgesia - methods Adult Analgesia, Obstetrical - methods Biological and medical sciences Childbirth & labor Clinical trials Double-Blind Method epidural Female Gynecology. Andrology. Obstetrics Humans induced labour Labor Pain - pathology Labor, Induced - methods labour outcome Medical sciences nulliparae Pain management Parity Pregnancy Treatment Outcome |
title | Acupuncture for pain relief during induced labour in nulliparae: a randomised controlled study |
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