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Disseminated intravascular coagulation due to IgM-mediated autoimmune hemolytic anemia

Disseminated intravascular coagulation (DIC) due to red cell hemolysis has been previously attributed to transfusion‐related hemolytic reactions, but not to autoimmune hemolytic anemia. We report a case of DIC in a child with complement‐fixing IgM‐mediated cold‐agglutinin autoimmune hemolysis, which...

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Bibliographic Details
Published in:Pediatric blood & cancer 2011-08, Vol.57 (2), p.329-331
Main Authors: Bleakly, N. Teresa, Fontaine, Magali J., Pate, Lisa L., Sutherland, Scott M., Jeng, Michael
Format: Article
Language:English
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Summary:Disseminated intravascular coagulation (DIC) due to red cell hemolysis has been previously attributed to transfusion‐related hemolytic reactions, but not to autoimmune hemolytic anemia. We report a case of DIC in a child with complement‐fixing IgM‐mediated cold‐agglutinin autoimmune hemolysis, which resulted in arterial thrombosis and gangrene of the upper and lower extremities. Pediatr Blood Cancer 2011; 57: 329–331. © 2011 Wiley‐Liss, Inc.
ISSN:1545-5009
1545-5017
1545-5017
DOI:10.1002/pbc.23024