Prevalence and Determinants of Incomplete Right Atrial Reverse Remodeling After Device Closure of Atrial Septal Defects

Whether the relief of chronic right atrial (RA) volume load by device closure of an atrial septal defect (ASD) normalizes RA size is unknown. The present study evaluated the prevalence and determinants of incomplete RA reverse remodeling (RAR) after ASD closure in adults. Transthoracic echocardiogra...

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Bibliographic Details
Published in:The American journal of cardiology 2011-07, Vol.108 (1), p.114-119
Main Authors: Fang, Fang, MM, PhD, Yu, Cheuk-Man, MD, Sanderson, John E., MD, Luo, Xiu-Xia, MB, Jiang, Xin, PhD, Yip, Gabriel Wai-Kwok, MD, Lam, Yat-Yin, MRCP
Format: Article
Language:English
Subjects:
Adult
Adults
Atrial Fibrillation - epidemiology
Atrial Fibrillation - etiology
Atrial Fibrillation - physiopathology
Balloon Occlusion - adverse effects
Balloon Occlusion - instrumentation
Biological and medical sciences
Cardiac arrhythmia
Cardiac Catheterization - adverse effects
Cardiac Catheterization - instrumentation
Cardiology. Vascular system
Cardiovascular
China - epidemiology
Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava
Disease Progression
Echocardiography, Transesophageal
Female
Follow-Up Studies
Heart
Heart Atria - diagnostic imaging
Heart Atria - physiopathology
Heart Septal Defects, Atrial - physiopathology
Heart Septal Defects, Atrial - surgery
Humans
Male
Medical sciences
Patients
Postoperative Complications
Prevalence
Retrospective Studies
Ultrasonic imaging
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Description
Summary:Whether the relief of chronic right atrial (RA) volume load by device closure of an atrial septal defect (ASD) normalizes RA size is unknown. The present study evaluated the prevalence and determinants of incomplete RA reverse remodeling (RAR) after ASD closure in adults. Transthoracic echocardiography was performed in 44 consecutive patients with secundum ASD (age 43 ± 17 years, 10 men) without a history of atrial arrhythmia shortly before and at 3 months after device closure of ASD. The pulmonary/systemic flow ratio was derived using invasive oximetry. The RA size had significantly decreased at 3 months of follow-up (RA volume index [RAVI] 52 ± 29 to 27 ± 17 ml/m2 , p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2011.03.007