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Hyperbaric oxygen therapy in a case of cholesterol crystal embolization

Prednisone at a daily dose of 25 mg (0.3 mg/[kg d]) and atorvastatin at a daily dose of 80 mg were started in addition to aspirin, clopidogrel, losartan, and amlodipine that the patient assumed at home. [...]narcotic therapy with tramadol chlorhydrate was added to relieve severe leg pain of which th...

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Bibliographic Details
Published in:The American journal of emergency medicine 2011-07, Vol.29 (6), p.694.e3-694.e6
Main Authors: Gurgo, Angela, MD, Valenti, Valentina, MD, Paneni, Francesco, MD, Passerini, Jasmine, MD, Di Vavo, Marta, MD, Calvieri, Camilla, MD, Cacchi, Claudio, MD, Bartolazzi, Armando, MD, Sabani, Anna, MD, Volpe, Massimo, MD
Format: Article
Language:English
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Summary:Prednisone at a daily dose of 25 mg (0.3 mg/[kg d]) and atorvastatin at a daily dose of 80 mg were started in addition to aspirin, clopidogrel, losartan, and amlodipine that the patient assumed at home. [...]narcotic therapy with tramadol chlorhydrate was added to relieve severe leg pain of which the patient had complained. Despite the progress of radiology and vascular surgery with their possible complications, CCE is still underdiagnosed; and its treatment is not codified. [...]it is very important that clinicians be aware of the risks of CCE after vascular procedure. The benefit of HBO are explained by hyperoxygenation of the hypoperfused tissue that induces significant positive changes in the repair process by enhancing fibroblastic replication, collagen synthesis, and neovascularization [19]. [...]hyperoxia has an anti-inflammatory effect in the vascular bed, reducing rolling and adhesion of polymorphonuclear cells in the microcirculation [20].
ISSN:0735-6757
1532-8171
DOI:10.1016/j.ajem.2010.05.023