A V-shaped cationic dye for nonlinear optical bioimaging

A symmetric cationic molecule with D-π-A(+)-π-D architecture was synthesized with high two-photon absorption cross-section (σ(2) ≈ 1140 GM). Application as a marker in fluorescence microscopy of living cells revealed its presence inside the cell staining vesicular shape organelles in the cytoplasm....

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Published in:Chemical communications (Cambridge, England) England), 2011-01, Vol.47 (26), p.7374-7376
Main Authors: Maçôas, Ermelinda, Marcelo, Gema, Pinto, Sandra, Cañeque, Tatiana, Cuadro, Ana M, Vaquero, Juan J, Martinho, José M G
Format: Article
Language:English
Subjects:
Approximation
Cationic
Coloring Agents - chemical synthesis
Coloring Agents - chemistry
Cross sections
Dyes
Fluorescence
HEK293 Cells
Humans
Markers
Microscopy
Microscopy, Fluorescence - methods
Optical Phenomena
Organelles
Quinolizines - chemical synthesis
Quinolizines - chemistry
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cited_by cdi_FETCH-LOGICAL-c385t-1e670d70cc8392c346c2d79ca2c0f1f20231bdf2603b57271235d3710694fa583
cites cdi_FETCH-LOGICAL-c385t-1e670d70cc8392c346c2d79ca2c0f1f20231bdf2603b57271235d3710694fa583
container_end_page 7376
container_issue 26
container_start_page 7374
container_title Chemical communications (Cambridge, England)
container_volume 47
creator Maçôas, Ermelinda
Marcelo, Gema
Pinto, Sandra
Cañeque, Tatiana
Cuadro, Ana M
Vaquero, Juan J
Martinho, José M G
description A symmetric cationic molecule with D-π-A(+)-π-D architecture was synthesized with high two-photon absorption cross-section (σ(2) ≈ 1140 GM). Application as a marker in fluorescence microscopy of living cells revealed its presence inside the cell staining vesicular shape organelles in the cytoplasm. Fluorescence lifetime imaging microscopy shows that it is also able to penetrate within the nucleus.
doi_str_mv 10.1039/c1cc12163d
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source Royal Society of Chemistry
subjects Approximation
Cationic
Coloring Agents - chemical synthesis
Coloring Agents - chemistry
Cross sections
Dyes
Fluorescence
HEK293 Cells
Humans
Markers
Microscopy
Microscopy, Fluorescence - methods
Optical Phenomena
Organelles
Quinolizines - chemical synthesis
Quinolizines - chemistry
title A V-shaped cationic dye for nonlinear optical bioimaging
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