Human Induced Pluripotent Stem Cells: A New Model for Schizophrenia?

Lack of patient tissue and relevant disease models have constrained progress toward discovering the causes of schizophrenia. Recently in Nature, Brennand et al. (2011) reprogram schizophrenia patient fibroblasts to derive four iPSC lines, perform subsequent neural differentiation, and provide early...

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Bibliographic Details
Published in:Cell stem cell 2011-05, Vol.8 (5), p.461-462
Main Authors: Buxbaum, Joseph D., Sklar, Pamela
Format: Article
Language:English
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Summary:Lack of patient tissue and relevant disease models have constrained progress toward discovering the causes of schizophrenia. Recently in Nature, Brennand et al. (2011) reprogram schizophrenia patient fibroblasts to derive four iPSC lines, perform subsequent neural differentiation, and provide early insights into a novel approach that may address these issues.
ISSN:1934-5909
1875-9777
DOI:10.1016/j.stem.2011.04.016