Bilateral symmetrical metachronous myxofibrosarcoma: a case report and review of the literature

Soft tissue sarcomas (STS) are rare. Affected patients are at increased risk of developing a second primary malignancy, particularly another primary STS. These rarely affect the extremities, tending to occur in the abdomen, head or neck. We describe a patient with myxofibrosarcoma of the buttock who...

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Bibliographic Details
Published in:Skeletal radiology 2011-08, Vol.40 (8), p.1085-1088
Main Authors: Picardo, Natasha Emma, Mann, Bhupinder, Whittingham-Jones, Paul, Shaerf, Dan, Skinner, John Andrew, Saifuddin, Asif
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biopsy, Needle
Buttocks
Case Report
Diagnosis, Differential
Female
Histiocytoma, Malignant Fibrous - diagnosis
Histiocytoma, Malignant Fibrous - pathology
Histiocytoma, Malignant Fibrous - radiotherapy
Humans
Imaging
Investigative techniques, diagnostic techniques (general aspects)
Magnetic Resonance Imaging
Medical sciences
Medicine
Medicine & Public Health
Metastasis
Middle Aged
Neoplasms, Second Primary - diagnosis
Neoplasms, Second Primary - pathology
Neoplasms, Second Primary - radiotherapy
Nuclear Medicine
Orthopedics
Osteoarticular system. Muscles
Pathology
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Radiology
Risk factors
Sarcoma
Soft Tissue Neoplasms - diagnosis
Soft Tissue Neoplasms - pathology
Soft Tissue Neoplasms - radiotherapy
Ultrasonography, Interventional
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Summary:Soft tissue sarcomas (STS) are rare. Affected patients are at increased risk of developing a second primary malignancy, particularly another primary STS. These rarely affect the extremities, tending to occur in the abdomen, head or neck. We describe a patient with myxofibrosarcoma of the buttock who developed a second primary tumour of the same histological type in the contralateral buttock thirty months after excision. Remarkably, the second tumour was symmetrical and there were no predisposing factors or evidence of metastatic spread. The second tumour was a significant size at presentation with encasement of the sciatic nerve. Awareness of the sarcoma patient's increased risk of developing a second tumour could lead to earlier diagnosis and improved outcome. A review of the literature on multiple soft tissue sarcomas is also presented.
ISSN:0364-2348
1432-2161
DOI:10.1007/s00256-011-1123-5