Lipofibromatosis in the finger of a child

Lipofibromatosis is a recently classified form of benign tumor in children; it is of non-specific clinical presentation and is seen mainly on the extremities. We report a case involving the index finger of a child. An 8-year-old boy consulted for a nodule on the palmar surface of the left index fing...

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Bibliographic Details
Published in:Annales de dermatologie et de vénéréologie 2011-05, Vol.138 (5), p.391-394
Main Authors: Mahé, E, Guéro, S, Fraitag, S
Format: Article
Language:fre
Subjects:
Actins - analysis
Biomarkers, Tumor - analysis
Child
Diagnosis, Differential
Fibroma - chemistry
Fibroma - diagnosis
Fibroma - pathology
Fibroma - surgery
Fingers - pathology
Humans
Lipoma - chemistry
Lipoma - diagnosis
Lipoma - pathology
Lipoma - surgery
Male
Neoplasm Proteins - analysis
Soft Tissue Neoplasms - chemistry
Soft Tissue Neoplasms - diagnosis
Soft Tissue Neoplasms - pathology
Soft Tissue Neoplasms - surgery
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Summary:Lipofibromatosis is a recently classified form of benign tumor in children; it is of non-specific clinical presentation and is seen mainly on the extremities. We report a case involving the index finger of a child. An 8-year-old boy consulted for a nodule on the palmar surface of the left index finger that had appeared 6 months earlier. The nodule, which adhered to the deeper skin, measured 1cm in diameter and was bluish and firm on palpation. Histological examination of the resected specimen revealed fatty tissue associated with a proliferation of spindle cells. Immunohistochemical analysis showed that certain of these cells expressed smooth muscle actin, suggesting partial myofibroblastic differentiation. A diagnosis of lipofibromatosis was made. Lipofibromatosis is a rare tumor. The main problem in terms of severity is its locally invasive development, which frequently causes problems for resection. Due to the age at onset, its course with deep invasion, the frequency of recurrence and the histological aspect, lipofibromatosis is classed as a form of childhood fibromatosis.
ISSN:0151-9638
DOI:10.1016/j.annder.2010.08.026