Effects of Echinaforce® treatment on ex vivo-stimulated blood cells

The herb Echinacea purpurea, also called purple coneflower, is regarded as an immune modulator. This study examined changes in cytokine production in blood samples from 30 volunteers before and during 8-day oral administration with an ethanolic extract of fresh Echinacea purpurea (Echinaforce®). Dai...

Full description

Saved in:
Bibliographic Details
Published in:Phytomedicine (Stuttgart) 2011-07, Vol.18 (10), p.826-831
Main Authors: Ritchie, M.R., Gertsch, J., Klein, P., Schoop, R.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Anti-inflammatory
Anti-Inflammatory Agents - pharmacology
Blood cells
Blood Cells - drug effects
Chemokines
Chemokines - blood
Chemokines - metabolism
Down-Regulation
Echinacea
Echinacea - chemistry
Ex vivo
Female
Herbal medicine
Humans
Immune System - drug effects
Immunomodulation
Interferons - blood
Interferons - metabolism
Interleukins - blood
Interleukins - metabolism
Male
Middle Aged
Physiological aspects
Plant Extracts - chemistry
Plant Extracts - pharmacology
Stress, Psychological
Tumor necrosis factor
Tumor Necrosis Factor-alpha - blood
Tumor Necrosis Factor-alpha - metabolism
Up-Regulation
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The herb Echinacea purpurea, also called purple coneflower, is regarded as an immune modulator. This study examined changes in cytokine production in blood samples from 30 volunteers before and during 8-day oral administration with an ethanolic extract of fresh Echinacea purpurea (Echinaforce®). Daily blood samples were ex vivo stimulated by LPS/SEB or Zymosan and analysed for a series of cytokines and haematological and metabolic parameters. Treatment reduced the proinflammatory mediators TNF-α and IL-1β by up to 24% (p
ISSN:0944-7113
1618-095X
DOI:10.1016/j.phymed.2011.05.011