A Comparative Study for the Assessment on Blood Flow Measurement Using Self-Mixing Laser Speckle Interferometer

We study a self-mixing laser diode (SM-LD) as a low-cost compact optical sensor for noninvasive blood flow measurement over the surface of the skin. We compare the SM-LD system with a commercially available Doppler flowmeter to assess the accuracy and feasibility of the SM-LD sensors for such applic...

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Bibliographic Details
Published in:IEEE transactions on instrumentation and measurement 2008-02, Vol.57 (2), p.355-363
Main Authors: Ozdemir, S.K., Ohno, I., Shinohara, S.
Format: Article
Language:English
Subjects:
Autocorrelation
Biomedical materials
Blood flow
Diode lasers
flow measurement
Flowmeters
Fluid flow measurement
In vitro
In vitro testing
In vivo
In vivo tests
laser diode (LD)
optical feedback
Optical interferometry
optical sensor
Optical sensors
self-mixing effect
Signal processing
Speckle
Surgical implants
velocimeter
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Summary:We study a self-mixing laser diode (SM-LD) as a low-cost compact optical sensor for noninvasive blood flow measurement over the surface of the skin. We compare the SM-LD system with a commercially available Doppler flowmeter to assess the accuracy and feasibility of the SM-LD sensors for such applications. For the SM-LD flowmeter, we apply two different signal processing methods: (1) the counting method, i.e., counting the intensity fluctuations of the signal to obtain a frequency value, and (2) the autocorrelation method, i.e., measuring the autocorrelation time of the signal. In vitro measurements show good agreement with the commercially available flowmeter. In vivo measurements performed on test subjects revealed that the autocorrelation technique shows much better results. The results of in vitro and in vivo studies and the comparison with the commercial flowmeter confirm the applicability of the SM-LD flowmeter.
ISSN:0018-9456
1557-9662
DOI:10.1109/TIM.2007.909473