Carbon nanopipettes for cell probes and intracellular injection

We developed integrated, carbon-based pipettes with nanoscale dimensions (CNP) that can probe cells with minimal intrusion, inject fluids into the cells, and concurrently carry out electrical measurements. Our manufacturing technique does not require cumbersome nanoassembly and is amenable to mass p...

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Bibliographic Details
Published in:Nanotechnology 2008-01, Vol.19 (1), p.015101-015101 (4)
Main Authors: Schrlau, Michael G, Falls, Erica M, Ziober, Barry L, Bau, Haim H
Format: Article
Language:English
Online Access:Get full text
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Summary:We developed integrated, carbon-based pipettes with nanoscale dimensions (CNP) that can probe cells with minimal intrusion, inject fluids into the cells, and concurrently carry out electrical measurements. Our manufacturing technique does not require cumbersome nanoassembly and is amenable to mass production. Using CNPs, we demonstrate the injection of reagents into cells with minimal intrusion and without inhibiting cell growth.
ISSN:0957-4484
1361-6528
DOI:10.1088/0957-4484/19/01/015101