Slow protein evolutionary rates are dictated by surface-core association

Why do certain proteins evolve much slower than others? We compared not only rates per protein, but also rates per position within individual proteins. For

Saved in:
Bibliographic Details
Published in:Proceedings of the National Academy of Sciences - PNAS 2011-07, Vol.108 (27), p.11151-11156
Main Authors: Tóth-Petróczy, Ágnes, Tawfik, Dan S
Format: Article
Language:English
Subjects:
Aggregation
Amino acids
Biological Sciences
Candida glabrata - chemistry
Candida glabrata - genetics
Databases, Protein
Datasets
Divergent evolution
Evolution
Evolution, Molecular
Fungal proteins
Fungal Proteins - chemistry
Fungal Proteins - genetics
Genetic mutation
Kluyveromyces - chemistry
Kluyveromyces - genetics
Models, Molecular
Mutation
Phylogeny
Protein folding
Protein Stability
Protein Structure, Tertiary
protein-protein interactions
Proteins
Saccharomyces
Saccharomyces - chemistry
Saccharomyces - genetics
Saccharomyces cerevisiae - chemistry
Saccharomyces cerevisiae - genetics
Saccharomyces cerevisiae Proteins - chemistry
Saccharomyces cerevisiae Proteins - genetics
Structural Homology, Protein
Time Factors
Yeasts
Yeasts - chemistry
Yeasts - classification
Yeasts - genetics
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Why do certain proteins evolve much slower than others? We compared not only rates per protein, but also rates per position within individual proteins. For
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.1015994108