The Outcomes of First Reoperation for Locoregionally Recurrent/Persistent Papillary Thyroid Carcinoma in Patients Who Initially Underwent Total Thyroidectomy and Remnant Ablation

Context: The primary treatment of locoregionally recurrent/persistent papillary thyroid cancer (PTC) is surgical removal by reoperation. However, there had been only limited number of reports on the outcome of reoperation. Objective: This study was to evaluate the efficacy of the first reoperation f...

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Bibliographic Details
Published in:The journal of clinical endocrinology and metabolism 2011-07, Vol.96 (7), p.2049-2056
Main Authors: Yim, Ji Hye, Kim, Won Bae, Kim, Eui Young, Kim, Won Gu, Kim, Tae Yong, Ryu, Jin-Sook, Gong, Gyungyub, Hong, Suck Joon, Shong, Young Kee
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Biological and medical sciences
Carcinoma, Papillary - pathology
Carcinoma, Papillary - surgery
Disease-Free Survival
Endocrinopathies
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
Humans
Male
Malignant tumors
Medical sciences
Middle Aged
Neoplasm Recurrence, Local - pathology
Neoplasm Recurrence, Local - surgery
Remission Induction
Reoperation
Retrospective Studies
Thyroid Neoplasms - pathology
Thyroid Neoplasms - surgery
Thyroid. Thyroid axis (diseases)
Thyroidectomy
Treatment Outcome
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Vertebrates: endocrinology
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Summary:Context: The primary treatment of locoregionally recurrent/persistent papillary thyroid cancer (PTC) is surgical removal by reoperation. However, there had been only limited number of reports on the outcome of reoperation. Objective: This study was to evaluate the efficacy of the first reoperation for locoregionally recurrent/persistent papillary thyroid carcinoma and the usefulness of stimulated thyroglobulin for evaluating efficacy of reoperation. Design and Settings: This was a retrospective observational cohort study in a tertiary referral hospital. Patients: A total of 83 patients, who underwent initial total thyroidectomy and nodal dissection with radioactive iodine remnant ablation, received reoperation for locoregionally recurrent/persistent PTC and were included in this study. Stimulated thyroglobulin levels were assessed before and after reoperation. Main Outcome Measures: We assessed biochemical remission (stimulated thyroglobulin
ISSN:0021-972X
1945-7197
DOI:10.1210/jc.2010-2298