Marjolin's ulcer associated with ulceration and chronic osteomyelitis

This report describes a 78-year old male patient with a chronic venous ulcer on his left leg for the past 24 years, complicated by a squamous-cell carcinoma. After staging of the disease, the treatment administered was amputation of the leg above the knee. Marjolin's ulcer consists of the malig...

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Bibliographic Details
Published in:Anais brasileiros de dermatología 2011-03, Vol.86 (2), p.366-369
Main Authors: Tavares, Ermelindo, Martinho, Gonçalo, Dores, José Alberto, Vera-Cruz, Frederico, Ferreira, Luís
Format: Article
Language:eng ; por
Subjects:
Aged
Amputation
Carcinoma, Squamous Cell - complications
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - surgery
Chronic Disease
Humans
Leg Ulcer - complications
Leg Ulcer - pathology
Leg Ulcer - surgery
Male
Osteomyelitis - complications
Osteomyelitis - pathology
Osteomyelitis - surgery
Skin Neoplasms - complications
Skin Neoplasms - pathology
Skin Neoplasms - surgery
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Summary:This report describes a 78-year old male patient with a chronic venous ulcer on his left leg for the past 24 years, complicated by a squamous-cell carcinoma. After staging of the disease, the treatment administered was amputation of the leg above the knee. Marjolin's ulcer consists of the malignant transformation of a chronic ulcerative lesion. It is a relatively rare phenomenon. The malignant tumor most commonly described in the literature is squamous cell carcinoma, followed by basal-cell carcinoma, sarcoma and melanoma. The pathogenesis of Marjolin's ulcer remains to be fully clarified.
ISSN:1806-4841
DOI:10.1590/S0365-05962011000200026