Preference‐based quality‐of‐life measures for neocortical epilepsy surgery

Summary Critical to decision analysis studies are measures of outcome utilities. In epilepsy surgery the benefit versus risk ratio is of particular interest in neocortical resections. Using the standard gamble, we measured preferences of 30 epilepsy patients for 10 outcome states specific to neocort...

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Bibliographic Details
Published in:Epilepsia (Copenhagen) 2011-05, Vol.52 (5), p.1018-1020
Main Authors: Knowlton, Robert C., Kar, Jitesh, Miller, Suzanne, Limdi, Nita, Elgavish, Rotem, Gilliam, Frank G., Riley, Kristen, Howell, Jennifer, Kilgore, Meredith
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Anticonvulsants - therapeutic use
Anticonvulsants. Antiepileptics. Antiparkinson agents
Biological and medical sciences
Cortex
Decision analysis
Decision Support Techniques
Disease-Free Survival
Epilepsy
Epilepsy - physiopathology
Epilepsy - psychology
Epilepsy - surgery
Female
Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy
Health Status
Humans
Injuries
Male
Medical sciences
Middle Aged
Models, Psychological
Neocortex - physiopathology
Neocortex - surgery
Nervous system (semeiology, syndromes)
Neurology
Neuropharmacology
Outcomes research
Patient Preference - psychology
Pharmacology. Drug treatments
Quality of Life
Risk Assessment
Seizures
Surgery
Surveys and Questionnaires
Treatment Outcome
Citations: Items that cite this one
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Summary:Summary Critical to decision analysis studies are measures of outcome utilities. In epilepsy surgery the benefit versus risk ratio is of particular interest in neocortical resections. Using the standard gamble, we measured preferences of 30 epilepsy patients for 10 outcome states specific to neocortical epilepsy surgery. Although considered preliminary, the findings suggest that the value of being seizure‐free may be greater than that of continued disabling seizures, even if some deficits typical of “eloquent” cortex injury are incurred with surgery. Seizure freedom achieved with polytherapy medical management may be less desirable than that achieved with surgery and monotherapy.
ISSN:0013-9580
1528-1167
DOI:10.1111/j.1528-1167.2011.03020.x