Numerical simulation and experimental validation of swirling flow in spiral vortex ventricular assist device

Spiral vortex ventricular assist device (SV-VAD) supports cardiac patients with refractory heart failure. Unfortunately, thrombus formation and risk of stroke due to flow complications may lead to aggravated conditions. The hemodynamics of a continuous flow in the ventricular chamber of a SV-VAD can...

Full description

Saved in:
Bibliographic Details
Published in:International journal of artificial organs 2010-12, Vol.33 (12), p.856-867
Main Authors: KIAN LOONG WONG, Kelvin, CHI POK CHEUNG, Sherman, YANG, William, JIYUAN TU
Format: Article
Language:English
Subjects:
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Computer Simulation
Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care
Heart-Assist Devices - adverse effects
Hemodynamics
Hemolysis
Intensive care medicine
Laser-Doppler Flowmetry
Materials Testing
Medical sciences
Models, Cardiovascular
Numerical Analysis, Computer-Assisted
Prosthesis Design
Reproducibility of Results
Stress, Mechanical
Thrombosis - blood
Thrombosis - etiology
Thrombosis - physiopathology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Spiral vortex ventricular assist device (SV-VAD) supports cardiac patients with refractory heart failure. Unfortunately, thrombus formation and risk of stroke due to flow complications may lead to aggravated conditions. The hemodynamics of a continuous flow in the ventricular chamber of a SV-VAD can be analyzed using numerical simulation. Particle image velocimetry and laser Doppler anemometry are utilized for validating the simulated spiral flow in a transparent acrylic SV-VAD replica based on its cross-sectional averaged axial and tangential velocities. After validation, the relationship between swirling flow and blood cell damage is established by evaluating flow effect on thrombosis due to high shear stress. Based on our analysis, stagnancy of the flow within the SV-VAD is insignificant and its low shear stress minimizes hemolysis.
ISSN:0391-3988
1724-6040
DOI:10.1177/039139881003301204