Carbonate and fluoride incorporation in synthetic apatites: Comparative effect on physico-chemical properties and in vitro bioactivity in fetal bovine serum

CO 3- and/or F-substituted apatites have been considered as potential bone substitution material for dental and orthopedic applications. The objective of this study was to compare physico-chemical properties and in vitro bioactivity in fetal bovine serum (FBS) of apatites containing CO 3 and/or F. T...

Full description

Saved in:
Bibliographic Details
Published in:Materials Science & Engineering C 2010-04, Vol.30 (3), p.423-430
Main Authors: Yao, Fang, LeGeros, Racquel Z.
Format: Article
Language:English
Subjects:
beta-Tricalcium phosphate (β-TCP)
Carbonate- and fluoride-substituted apatite (CFA)
Crystallinity
In vitro bioactivity
Solubility
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:CO 3- and/or F-substituted apatites have been considered as potential bone substitution material for dental and orthopedic applications. The objective of this study was to compare physico-chemical properties and in vitro bioactivity in fetal bovine serum (FBS) of apatites containing CO 3 and/or F. The results showed that CO 3 and F in apatites have opposite effects on crystallinity and solubility. Calcium deficient hydroxyapatite (HA) and F-substituted apatite (FA) partially transformed to beta-tricalcium phosphate (β-TCP) at temperature 950 °C. After immersion in FBS for 10 days, calcium deficient HA, FA, and CO 3-substituted apatite (CHA) and CO 3- and F-substituted apatite (CFA) pellet surfaces all showed formation of apatite.
ISSN:0928-4931
1873-0191
DOI:10.1016/j.msec.2009.12.011